Electrocorticographic amplitude predicts finger positions during slow grasping motions of the hand

Soumyadipta Acharya, Matthew S. Fifer, Heather L. Benz, Nathan E Crone, Nitish V Thakor

Research output: Contribution to journalArticle

Abstract

Four human subjects undergoing subdural electrocorticography for epilepsy surgery engaged in a range of finger and hand movements. We observed that the amplitudes of the low-pass filtered electrocorticogram (ECoG), also known as the local motor potential (LMP), over specific peri-Rolandic electrodes were correlated (p <0.001) with the position of individual fingers as the subjects engaged in slow and deliberate grasping motions. A generalized linear model (GLM) of the LMP amplitudes from those electrodes yielded predictions for positions of the fingers that had a strong congruence with the actual finger positions (correlation coefficient, r; median = 0.51, maximum = 0.91), during displacements of up to 10 cm at the fingertips. For all the subjects, decoding filters trained on data from any given session were remarkably robust in their prediction performance across multiple sessions and days, and were invariant with respect to changes in wrist angle, elbow flexion and hand placement across these sessions (median r = 0.52, maximum r = 0.86). Furthermore, a reasonable prediction accuracy for grasp aperture was achievable with as few as three electrodes in all subjects (median r = 0.49; maximum r = 0.90). These results provide further evidence for the feasibility of robust and practical ECoG-based control of finger movements in upper extremity prosthetics.

Original languageEnglish (US)
Article number046002
JournalJournal of Neural Engineering
Volume7
Issue number4
DOIs
StatePublished - 2010

Fingerprint

Fingers
Hand
Electrodes
Prosthetics
Surgery
Decoding
Hand Strength
Elbow
Wrist
Upper Extremity
Linear Models
Epilepsy

ASJC Scopus subject areas

  • Biomedical Engineering
  • Cellular and Molecular Neuroscience

Cite this

Electrocorticographic amplitude predicts finger positions during slow grasping motions of the hand. / Acharya, Soumyadipta; Fifer, Matthew S.; Benz, Heather L.; Crone, Nathan E; Thakor, Nitish V.

In: Journal of Neural Engineering, Vol. 7, No. 4, 046002, 2010.

Research output: Contribution to journalArticle

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