TY - JOUR
T1 - Electrical and anatomical imaging of arrhythmogenic substrates for scar-related ventricular tachycardia
AU - Gharbia, Omar A.
AU - Tao, Susumu
AU - Lardo, Albert C.
AU - Halperin, Henry
AU - Wang, Linwei
N1 - Funding Information:
This work was supported by the National Institute of Heart, Lung, and Blood of the National Institutes of Health under Award R21Hl125998.
Publisher Copyright:
© 2017 IEEE Computer Society. All rights reserved.
PY - 2017
Y1 - 2017
N2 - Sustained ventricular tachycardia (VT) often involves a reentry circuit formed by narrow channels of surviving tissue within the scar. Catheter ablation is an effective technique to intercept the circuit by targeting these critical channels. The success of VT ablation relies on our ability to assess the mechanism of the VT circuit and identify the location of the ablation targets. This study aims to analyze the VT substrate using high-resolution anatomical and electrical imaging techniques including contact EGM mapping, contrast-enhanced cardiac magnetic resonance (CMR) imaging, and noninvasive electrocardio-graphic (ECG) imaging. The results indicate that joint electro-anatomical analysis could reveal critical isthmus of the VT circuit. In addition, ECG-imaging was able to identify sites of a scar and signal fractionation visually consistent with the other two modalities, and the reconstructed VT circuit revealed an exit around the critical site identified by combined CMR-EGM data.
AB - Sustained ventricular tachycardia (VT) often involves a reentry circuit formed by narrow channels of surviving tissue within the scar. Catheter ablation is an effective technique to intercept the circuit by targeting these critical channels. The success of VT ablation relies on our ability to assess the mechanism of the VT circuit and identify the location of the ablation targets. This study aims to analyze the VT substrate using high-resolution anatomical and electrical imaging techniques including contact EGM mapping, contrast-enhanced cardiac magnetic resonance (CMR) imaging, and noninvasive electrocardio-graphic (ECG) imaging. The results indicate that joint electro-anatomical analysis could reveal critical isthmus of the VT circuit. In addition, ECG-imaging was able to identify sites of a scar and signal fractionation visually consistent with the other two modalities, and the reconstructed VT circuit revealed an exit around the critical site identified by combined CMR-EGM data.
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U2 - 10.22489/CinC.2017.042-345
DO - 10.22489/CinC.2017.042-345
M3 - Conference article
AN - SCOPUS:85045124813
SN - 2325-8861
VL - 44
SP - 1
EP - 4
JO - Computing in Cardiology
JF - Computing in Cardiology
T2 - 44th Computing in Cardiology Conference, CinC 2017
Y2 - 24 September 2017 through 27 September 2017
ER -