Electric tempest in a teacup: The tea leaf analogy to microfluidic blood plasma separation

Leslie Y. Yeo; James R. Friend; Dian R. Arifin

doi:10.1063/1.2345590

Electric tempest in a teacup: The tea leaf analogy to microfluidic blood plasma separation

Leslie Y. Yeo, James R. Friend, Dian R. Arifin

School of Medicine

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

In a similar fashion to Einstein's tea leaf paradox, the rotational liquid flow induced by ionic wind above a liquid surface can trap suspended microparticles by a helical motion, spinning them down towards a bottom stagnation point. The motion is similar to Batchelor [Q. J. Mech. Appl. Math. 4, 29 (1951)] flows occurring between stationary and rotating disks and arises due to a combination of the primary azimuthal and secondary bulk meridional recirculation that produces a centrifugal and enhanced inward radial force near the chamber bottom. The technology is thus useful for microfluidic particle trapping/concentration; the authors demonstrate its potential for rapid erythrocyte/blood plasma separation for miniaturized medical diagnostic kits.

Original language	English (US)
Article number	103516
Journal	Applied Physics Letters
Volume	89
Issue number	10
DOIs	https://doi.org/10.1063/1.2345590
State	Published - 2006

ASJC Scopus subject areas

Physics and Astronomy (miscellaneous)

Access to Document

10.1063/1.2345590

Cite this

@article{5e3b03b67b9040839105fc611f8481e0,

title = "Electric tempest in a teacup: The tea leaf analogy to microfluidic blood plasma separation",

abstract = "In a similar fashion to Einstein's tea leaf paradox, the rotational liquid flow induced by ionic wind above a liquid surface can trap suspended microparticles by a helical motion, spinning them down towards a bottom stagnation point. The motion is similar to Batchelor [Q. J. Mech. Appl. Math. 4, 29 (1951)] flows occurring between stationary and rotating disks and arises due to a combination of the primary azimuthal and secondary bulk meridional recirculation that produces a centrifugal and enhanced inward radial force near the chamber bottom. The technology is thus useful for microfluidic particle trapping/concentration; the authors demonstrate its potential for rapid erythrocyte/blood plasma separation for miniaturized medical diagnostic kits.",

author = "Yeo, {Leslie Y.} and Friend, {James R.} and Arifin, {Dian R.}",

year = "2006",

doi = "10.1063/1.2345590",

language = "English (US)",

volume = "89",

journal = "Applied Physics Letters",

issn = "0003-6951",

publisher = "American Institute of Physics Publising LLC",

number = "10",

}

TY - JOUR

T1 - Electric tempest in a teacup

T2 - The tea leaf analogy to microfluidic blood plasma separation

AU - Yeo, Leslie Y.

AU - Friend, James R.

AU - Arifin, Dian R.

PY - 2006

Y1 - 2006

N2 - In a similar fashion to Einstein's tea leaf paradox, the rotational liquid flow induced by ionic wind above a liquid surface can trap suspended microparticles by a helical motion, spinning them down towards a bottom stagnation point. The motion is similar to Batchelor [Q. J. Mech. Appl. Math. 4, 29 (1951)] flows occurring between stationary and rotating disks and arises due to a combination of the primary azimuthal and secondary bulk meridional recirculation that produces a centrifugal and enhanced inward radial force near the chamber bottom. The technology is thus useful for microfluidic particle trapping/concentration; the authors demonstrate its potential for rapid erythrocyte/blood plasma separation for miniaturized medical diagnostic kits.

AB - In a similar fashion to Einstein's tea leaf paradox, the rotational liquid flow induced by ionic wind above a liquid surface can trap suspended microparticles by a helical motion, spinning them down towards a bottom stagnation point. The motion is similar to Batchelor [Q. J. Mech. Appl. Math. 4, 29 (1951)] flows occurring between stationary and rotating disks and arises due to a combination of the primary azimuthal and secondary bulk meridional recirculation that produces a centrifugal and enhanced inward radial force near the chamber bottom. The technology is thus useful for microfluidic particle trapping/concentration; the authors demonstrate its potential for rapid erythrocyte/blood plasma separation for miniaturized medical diagnostic kits.

UR - http://www.scopus.com/inward/record.url?scp=33748517224&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748517224&partnerID=8YFLogxK

U2 - 10.1063/1.2345590

DO - 10.1063/1.2345590

M3 - Article

AN - SCOPUS:33748517224

VL - 89

JO - Applied Physics Letters

JF - Applied Physics Letters

SN - 0003-6951

IS - 10

M1 - 103516

ER -

Electric tempest in a teacup: The tea leaf analogy to microfluidic blood plasma separation

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this