Elastography

A quantitative method for imaging the elasticity of biological tissues

J. Ophir, I. Céspedes, H. Ponnekanti, Youseph Yazdi, X. Li

Research output: Contribution to journalArticle

Abstract

We describe a new method for quantitative imaging of strain and elastic modulus distributions in soft tissues. The method is based on external tissue compression, with subsequent computation of the strain profile along the transducer axis, which is derived from cross-correlation analysis of pre- and post-compression A-line pairs. The strain profile can then be converted to an elastic modulus profile by measuring the stresses applied by the compressing device and applying certain corrections for the nonuniform stress field. We report initial results of serveral phantom and excised animal tissue experiments which demonstrate the ability of this technique to quantitatively image strain and elastic modulus distributions with good resolution, sensitivity and with diminished speckle. We discuss several potential clinical uses of this technique.

Original languageEnglish (US)
Pages (from-to)111-134
Number of pages24
JournalUltrasonic Imaging
Volume13
Issue number2
DOIs
StatePublished - 1991
Externally publishedYes

Fingerprint

Elasticity Imaging Techniques
Elastic Modulus
modulus of elasticity
elastic properties
profiles
Transducers
compressing
cross correlation
stress distribution
animals
transducers
Equipment and Supplies
sensitivity

Keywords

  • Breast scanning
  • cancer detection
  • compliance
  • compressibility
  • elastic modulus
  • elasticity
  • elastogram
  • elastography
  • imaging
  • soft tissue
  • strain
  • stress
  • ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Acoustics and Ultrasonics

Cite this

Elastography : A quantitative method for imaging the elasticity of biological tissues. / Ophir, J.; Céspedes, I.; Ponnekanti, H.; Yazdi, Youseph; Li, X.

In: Ultrasonic Imaging, Vol. 13, No. 2, 1991, p. 111-134.

Research output: Contribution to journalArticle

Ophir, J. ; Céspedes, I. ; Ponnekanti, H. ; Yazdi, Youseph ; Li, X. / Elastography : A quantitative method for imaging the elasticity of biological tissues. In: Ultrasonic Imaging. 1991 ; Vol. 13, No. 2. pp. 111-134.
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