TY - GEN
T1 - Efficient large deformation registration via geodesics on a learned manifold of images
AU - Hamm, Jihun
AU - Davatzikos, Christos
AU - Verma, Ragini
N1 - Funding Information:
This work was supported by NIH grants R01-MH079938 and R01-AG014971.
PY - 2009
Y1 - 2009
N2 - Geodesic registration methods have been used to solve the large deformation registration problems, which are hard to solve with conventional registration methods. However, analytically defined geodesics may not coincide with anatomically optimal paths of registration. In this paper we propose a novel and efficient method for large deformation registration by learning the underlying structure of the data using a manifold learning technique. In this method a large deformation between two images is decomposed into a series of small deformations along the shortest path on the graph that approximates the metric structure of data. Furthermore, the graph representation allows us to estimate the optimal group template by minimizing geodesic distances. We demonstrate the advantages of the proposed method with synthetic 2D images and real 3D mice brain volumes.
AB - Geodesic registration methods have been used to solve the large deformation registration problems, which are hard to solve with conventional registration methods. However, analytically defined geodesics may not coincide with anatomically optimal paths of registration. In this paper we propose a novel and efficient method for large deformation registration by learning the underlying structure of the data using a manifold learning technique. In this method a large deformation between two images is decomposed into a series of small deformations along the shortest path on the graph that approximates the metric structure of data. Furthermore, the graph representation allows us to estimate the optimal group template by minimizing geodesic distances. We demonstrate the advantages of the proposed method with synthetic 2D images and real 3D mice brain volumes.
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U2 - 10.1007/978-3-642-04268-3_84
DO - 10.1007/978-3-642-04268-3_84
M3 - Conference contribution
C2 - 20426047
AN - SCOPUS:79551685631
SN - 3642042678
SN - 9783642042676
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 680
EP - 687
BT - Medical Image Computing and Computer-Assisted Intervention - MICCAI 2009 - 12th International Conference, Proceedings
T2 - 12th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2009
Y2 - 20 September 2009 through 24 September 2009
ER -