Trifluoroacetic acid has been found to be an efficient and non-oxidative catalyst for the epimerization of pyrene and other C-nucleosides in dichloromethane at ambient temperature. Aspects of the epimerization mechanism are also elucidated.
- Pyrene nucleoside
- Trifluoroacetic acid and dichloromethane
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry