Efficacy of repetitive transcranial magnetic stimulation (rTMS) in the treatment of affective disorders

Thomas E. Schlaepfer, Markus Kosel, Charles B. Nemeroff

Research output: Contribution to journalArticle

Abstract

Transcranialmagnetic Stimulation (TMS) is a relatively noninvasive technique to interfere with the function of small corticalareas through currents induced by alternating magnetic fields emanating from a handheld coilplaced directly above the targeted area. This techniquehas clear effects on a whole range of measures of brain function and has become an important research toolin neuropsychiatry. More recently, TMS has been studied in psychiatry mainly to assess its putativetherapeutic effectsin treatment refractory major depression.Most studies indicate that both low-frequency TMS and higher (20 Hz) frequency repetitive TMS may have some antidepressant properties. However, definite therapeutic effects of clinicalsignificancestillremain to be demonstrated.

Original languageEnglish (US)
Pages (from-to)201-205
Number of pages5
JournalNeuropsychopharmacology
Volume28
Issue number2
DOIs
StatePublished - Dec 2003

Keywords

  • Major depression
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Pharmacology
  • Psychiatry and Mental health

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