TY - JOUR
T1 - Efficacy of prostate-specific antigen and magnetic resonance imaging in staging stage C adenocarcinoma of the prostate
AU - Schiebler, Mark L.
AU - Yankaskas, Bonnie C.
AU - Tempany, Clare
AU - Holtz, Patrice
AU - Zerhouni, Elias
PY - 1992/8
Y1 - 1992/8
N2 - Objectives. The authors compared the two most common presurgical tests now used for the preoperative staging of adenocarcinoma of the prostate, prostate-specific antigen (PSA) and magnetic resonance imaging (MRI). Methods. One hundred consecutive radical retropubic prostatectomy patients were imaged at 1.5 Tesla before surgery with routine T1-weighted and T2-weighted transaxial images. The images were analyzed by two experienced radiologists for evidence of extracapsular disease. Radiologists rated each gland on a scale of 0 to 100 for the percentage likelihood of extracapsular disease based on its MRI appearance. Receiver operator characteristic (ROC) curves were plotted, and areas were calculated for the two radiologists and the preoperative PSA values. Results. Comparison of the areas of the ROC curves generated from the two radiologists and those from the preoperative PSA values showed no statistical difference. Conclusions. In this series, radiologic interpretation of body coil MRI studies in those patients chosen for a radical retropubic prostatectomy was no better in staging adenocarcinoma of the prostate than simply using the preoperative PSA values.
AB - Objectives. The authors compared the two most common presurgical tests now used for the preoperative staging of adenocarcinoma of the prostate, prostate-specific antigen (PSA) and magnetic resonance imaging (MRI). Methods. One hundred consecutive radical retropubic prostatectomy patients were imaged at 1.5 Tesla before surgery with routine T1-weighted and T2-weighted transaxial images. The images were analyzed by two experienced radiologists for evidence of extracapsular disease. Radiologists rated each gland on a scale of 0 to 100 for the percentage likelihood of extracapsular disease based on its MRI appearance. Receiver operator characteristic (ROC) curves were plotted, and areas were calculated for the two radiologists and the preoperative PSA values. Results. Comparison of the areas of the ROC curves generated from the two radiologists and those from the preoperative PSA values showed no statistical difference. Conclusions. In this series, radiologic interpretation of body coil MRI studies in those patients chosen for a radical retropubic prostatectomy was no better in staging adenocarcinoma of the prostate than simply using the preoperative PSA values.
KW - Adenocarcinoma of the prostate
KW - Magnetic resonance imaging
KW - Prostate-specific antigen
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U2 - 10.1097/00004424-199208000-00002
DO - 10.1097/00004424-199208000-00002
M3 - Article
C2 - 1385355
AN - SCOPUS:0026648479
SN - 0020-9996
VL - 27
SP - 575
EP - 577
JO - Investigative radiology
JF - Investigative radiology
IS - 8
ER -