Efficacy of milk versus yogurt offered as part of a mixed diet in acute noncholera diarrhea among malnourished children

S. Bhatnagar, K. D. Singh, S. Sazawal, S. K. Saxena, M. K. Bhan

Research output: Contribution to journalArticle

Abstract

We compared the clinical outcome of acute diarrhea in 96 malnourished boys (aged 4 to 47 months) receiving full-strength milk compared with yogurt offered as part of a mixed diet. All had weight for height less than or equal to 80% of the National Centre for Health Statistics median. They were randomly assigned to receive milk formula (MF; 67 cal/100 ml) or yogurt formula (YF; prepared from the same milk formula) at the rate of 120 ml/kg body weight in seven divided feedings. Stool-reducing substances (>1%) were detected more frequently in the MF group, and the differences were significant for day 3 of the study (p = 0.04). However, the geometric mean (95% confidence interval) of the total stool weight (gm/kg) during 0 to 72 hours (MF 128.8 [103, 161.4]; YF 110.9 [87, 142.2]) was comparable (p = 0.37), as was the median (range) duration of diarrhea (hours) (MF 45 [4, 183]; YF 52 [7, 173] p = 0.94). The treatment failure rates in the MF (8.2%) and YF (6.3%) groups were also similar (p = 0.67). The children consuming milk had higher median percent weight gain at the end of 72 hours of the study (p = 0.04) and at recovery (p = 0.02). Routine substitution of yogurt as small frequent feedings as an addition for semisolid food to malnourished children with acute diarrhea does not achieve any significant clinical benefit versus milk.

Original languageEnglish (US)
Pages (from-to)999-1003
Number of pages5
JournalJournal of Pediatrics
Volume132
Issue number6
DOIs
StatePublished - Jan 1 1998

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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