Efficacy of introducing a checklist to reduce central venous line associated bloodstream infections in the ICU caring for adult patients

Dominic Wichmann, Cristina E. Belmar Campos, Stephan Ehrhardt, Timo Kock, Claudia Weber, Holger Rohde, Stefan Kluge

Research output: Contribution to journalArticle

Abstract

Background: Central line-associated bloodstream infections (CLABSI) are a major source of sepsis in modern intensive care medicine. Some years ago bundle interventions have been introduced to reduce CLABSI. The use of checklists may be an additional tool to improve the effect of these bundles even in highly specialized institutions. In this study we investigate if the introduction of a checklist reduces the frequency of CLABSI. Methods: During the study period from October 2011 to September 2012, we investigated the effect of implementing a checklist for the placement of central venous lines (CVL). Patients were allocated either to the checklist group or to the control group, roughly in a 1:2 ratio. The frequency of CLABSI was compared between the two groups. Results: During the study period 4416 CVL were inserted; 1518 in the checklist group and 2898 in the control group. The use of the checklist during CVL placement resulted in a lower CLABSI frequency. The incidence in the checklist group was 3.8 per 1000 catheter days as compared to 5.9 per 1000 catheter days in the control group (IRR = 0.57; p = 0.001). The use of the checklist also reduced the frequency of catheter colonisation significantly, 36.3 per 1000 catheter days in the checklist group vs 21.2 per 1000 catheter days in the control group, respectively (IRR = 0.58; p < 0.001). Conclusion: The introduction of a checklist to improve the adherence to hygiene standards while placement of central venous lines reduced the frequency of infections significantly.

Original languageEnglish (US)
Article number267
JournalBMC Infectious Diseases
Volume18
Issue number1
DOIs
StatePublished - Jun 8 2018

Fingerprint

Checklist
Infection
Catheters
Control Groups
Critical Care
Hygiene
Sepsis
Medicine
Incidence

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

Efficacy of introducing a checklist to reduce central venous line associated bloodstream infections in the ICU caring for adult patients. / Wichmann, Dominic; Belmar Campos, Cristina E.; Ehrhardt, Stephan; Kock, Timo; Weber, Claudia; Rohde, Holger; Kluge, Stefan.

In: BMC Infectious Diseases, Vol. 18, No. 1, 267, 08.06.2018.

Research output: Contribution to journalArticle

Wichmann, Dominic ; Belmar Campos, Cristina E. ; Ehrhardt, Stephan ; Kock, Timo ; Weber, Claudia ; Rohde, Holger ; Kluge, Stefan. / Efficacy of introducing a checklist to reduce central venous line associated bloodstream infections in the ICU caring for adult patients. In: BMC Infectious Diseases. 2018 ; Vol. 18, No. 1.
@article{c921f6bd970340d4841d50b9353aa749,
title = "Efficacy of introducing a checklist to reduce central venous line associated bloodstream infections in the ICU caring for adult patients",
abstract = "Background: Central line-associated bloodstream infections (CLABSI) are a major source of sepsis in modern intensive care medicine. Some years ago bundle interventions have been introduced to reduce CLABSI. The use of checklists may be an additional tool to improve the effect of these bundles even in highly specialized institutions. In this study we investigate if the introduction of a checklist reduces the frequency of CLABSI. Methods: During the study period from October 2011 to September 2012, we investigated the effect of implementing a checklist for the placement of central venous lines (CVL). Patients were allocated either to the checklist group or to the control group, roughly in a 1:2 ratio. The frequency of CLABSI was compared between the two groups. Results: During the study period 4416 CVL were inserted; 1518 in the checklist group and 2898 in the control group. The use of the checklist during CVL placement resulted in a lower CLABSI frequency. The incidence in the checklist group was 3.8 per 1000 catheter days as compared to 5.9 per 1000 catheter days in the control group (IRR = 0.57; p = 0.001). The use of the checklist also reduced the frequency of catheter colonisation significantly, 36.3 per 1000 catheter days in the checklist group vs 21.2 per 1000 catheter days in the control group, respectively (IRR = 0.58; p < 0.001). Conclusion: The introduction of a checklist to improve the adherence to hygiene standards while placement of central venous lines reduced the frequency of infections significantly.",
author = "Dominic Wichmann and {Belmar Campos}, {Cristina E.} and Stephan Ehrhardt and Timo Kock and Claudia Weber and Holger Rohde and Stefan Kluge",
year = "2018",
month = "6",
day = "8",
doi = "10.1186/s12879-018-3178-6",
language = "English (US)",
volume = "18",
journal = "BMC Infectious Diseases",
issn = "1471-2334",
publisher = "BioMed Central",
number = "1",

}

TY - JOUR

T1 - Efficacy of introducing a checklist to reduce central venous line associated bloodstream infections in the ICU caring for adult patients

AU - Wichmann, Dominic

AU - Belmar Campos, Cristina E.

AU - Ehrhardt, Stephan

AU - Kock, Timo

AU - Weber, Claudia

AU - Rohde, Holger

AU - Kluge, Stefan

PY - 2018/6/8

Y1 - 2018/6/8

N2 - Background: Central line-associated bloodstream infections (CLABSI) are a major source of sepsis in modern intensive care medicine. Some years ago bundle interventions have been introduced to reduce CLABSI. The use of checklists may be an additional tool to improve the effect of these bundles even in highly specialized institutions. In this study we investigate if the introduction of a checklist reduces the frequency of CLABSI. Methods: During the study period from October 2011 to September 2012, we investigated the effect of implementing a checklist for the placement of central venous lines (CVL). Patients were allocated either to the checklist group or to the control group, roughly in a 1:2 ratio. The frequency of CLABSI was compared between the two groups. Results: During the study period 4416 CVL were inserted; 1518 in the checklist group and 2898 in the control group. The use of the checklist during CVL placement resulted in a lower CLABSI frequency. The incidence in the checklist group was 3.8 per 1000 catheter days as compared to 5.9 per 1000 catheter days in the control group (IRR = 0.57; p = 0.001). The use of the checklist also reduced the frequency of catheter colonisation significantly, 36.3 per 1000 catheter days in the checklist group vs 21.2 per 1000 catheter days in the control group, respectively (IRR = 0.58; p < 0.001). Conclusion: The introduction of a checklist to improve the adherence to hygiene standards while placement of central venous lines reduced the frequency of infections significantly.

AB - Background: Central line-associated bloodstream infections (CLABSI) are a major source of sepsis in modern intensive care medicine. Some years ago bundle interventions have been introduced to reduce CLABSI. The use of checklists may be an additional tool to improve the effect of these bundles even in highly specialized institutions. In this study we investigate if the introduction of a checklist reduces the frequency of CLABSI. Methods: During the study period from October 2011 to September 2012, we investigated the effect of implementing a checklist for the placement of central venous lines (CVL). Patients were allocated either to the checklist group or to the control group, roughly in a 1:2 ratio. The frequency of CLABSI was compared between the two groups. Results: During the study period 4416 CVL were inserted; 1518 in the checklist group and 2898 in the control group. The use of the checklist during CVL placement resulted in a lower CLABSI frequency. The incidence in the checklist group was 3.8 per 1000 catheter days as compared to 5.9 per 1000 catheter days in the control group (IRR = 0.57; p = 0.001). The use of the checklist also reduced the frequency of catheter colonisation significantly, 36.3 per 1000 catheter days in the checklist group vs 21.2 per 1000 catheter days in the control group, respectively (IRR = 0.58; p < 0.001). Conclusion: The introduction of a checklist to improve the adherence to hygiene standards while placement of central venous lines reduced the frequency of infections significantly.

UR - http://www.scopus.com/inward/record.url?scp=85048286211&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85048286211&partnerID=8YFLogxK

U2 - 10.1186/s12879-018-3178-6

DO - 10.1186/s12879-018-3178-6

M3 - Article

C2 - 29884118

AN - SCOPUS:85048286211

VL - 18

JO - BMC Infectious Diseases

JF - BMC Infectious Diseases

SN - 1471-2334

IS - 1

M1 - 267

ER -