TY - JOUR
T1 - Efficacy and Tolerability of a Novel Biopsy Device for Removing Benign Epidermal Skin Lesions
AU - Yang, Steven Hoseong
AU - Qi, Ji
AU - Esandrio, Jessica
AU - Leung, Sherry
AU - Taube, Janis M.
AU - Garza, Luis A.
AU - Allen, Robert
AU - Kang, Sewon
AU - Chien, Anna L.
N1 - Publisher Copyright:
© 2015 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - BACKGROUND The shave biopsy using a razor with an open blade is the current standard of care for sampling superficial skin lesions. OBJECTIVE To enhance safety, the authors developed a novel biopsy device with a closed blade design for removing the epidermal layer of skin and evaluated against the open razor blade for tolerability, scarring, and accuracy in histological diagnosis. MATERIALS AND METHODS Shave biopsies were performed using the novel device or razor blade on benign epidermal skin lesions in 10 patients on comparable body parts. Digital photography, colorimetry, scar scale evaluations, and questionnaires were used to evaluate the efficacy and tolerability of the devices. RESULTS For all patients, accurate histological diagnoses were made regardless of device type. No statistically significant differences were detected between the novel device and razor blade in terms of scar scale assessments, colorimetry, and questionnaire responses. Both patients and the participating dermatologist reported satisfaction with the safety and performance of the novel device. No injuries to the provider occurred with either instrument. CONCLUSION The rotating sphere biopsy device is a potential alternative to the razor blade with comparable tolerability, scarring, and accuracy in histological diagnoses, offering improved safety for patients and health care providers.
AB - BACKGROUND The shave biopsy using a razor with an open blade is the current standard of care for sampling superficial skin lesions. OBJECTIVE To enhance safety, the authors developed a novel biopsy device with a closed blade design for removing the epidermal layer of skin and evaluated against the open razor blade for tolerability, scarring, and accuracy in histological diagnosis. MATERIALS AND METHODS Shave biopsies were performed using the novel device or razor blade on benign epidermal skin lesions in 10 patients on comparable body parts. Digital photography, colorimetry, scar scale evaluations, and questionnaires were used to evaluate the efficacy and tolerability of the devices. RESULTS For all patients, accurate histological diagnoses were made regardless of device type. No statistically significant differences were detected between the novel device and razor blade in terms of scar scale assessments, colorimetry, and questionnaire responses. Both patients and the participating dermatologist reported satisfaction with the safety and performance of the novel device. No injuries to the provider occurred with either instrument. CONCLUSION The rotating sphere biopsy device is a potential alternative to the razor blade with comparable tolerability, scarring, and accuracy in histological diagnoses, offering improved safety for patients and health care providers.
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U2 - 10.1097/DSS.0000000000000530
DO - 10.1097/DSS.0000000000000530
M3 - Article
C2 - 26506067
AN - SCOPUS:84946066079
SN - 1076-0512
VL - 41
SP - 1264
EP - 1273
JO - Dermatologic Surgery
JF - Dermatologic Surgery
IS - 11
ER -