Effects of warfarin on blood pressure in men with diabetes and hypertension--a longitudinal study.

Mary Ann Lim, Shahzad Shafique, Sein Yin See, Faisal N. Khan, Chirag R. Parikh, Aldo J. Peixoto

Research output: Contribution to journalArticle

Abstract

Warfarin causes extensive vascular calcification leading to increased systolic blood pressure and pulse pressure in rats, may be associated with increased valvular and coronary calcifications in man, and possibly worsens hypertension in high-risk patients, particularly in those with diabetes mellitus or uncontrolled hypertension. The authors evaluated blood pressure and intensity of antihypertensive therapy over 36 months in a cohort of 58 patients with diabetes and hypertension on warfarin and 58 control subjects with diabetes and hypertension not on warfarin. The results demonstrate that warfarin therapy at conventional doses does not increase systolic blood pressure or pulse pressure in patients with diabetes and hypertension.

Original languageEnglish (US)
Pages (from-to)256-258
Number of pages3
JournalJournal of clinical hypertension (Greenwich, Conn.)
Volume9
Issue number4
DOIs
StatePublished - Apr 2007
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

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