Effects of temperature on glycosyltransferase activity in the plasma membrane of L cells

Valerie Petit Setlow, Stephen Roth, Michael Edidin

Research output: Contribution to journalArticlepeer-review

Abstract

Derivatives of mouse L cells, cl-ld and LM, are capable of self- or cis-glycosylation. This reaction appears to require interaction of transferase and acceptor by collision in the course of diffusion in the plane of the membrane. The effect of temperature on glycosylation indicates this may well be the case since anomalies in the rate of the reaction, unexpectedly high rates, are found at temperatures below 20 °C. The anomalies are similar to those previously found for lateral diffusion of surface antigens in these cells. Such anomalies are not found for the transfer of galactose by the cells' enzymes to a water-soluble acceptor.

Original languageEnglish (US)
Pages (from-to)55-61
Number of pages7
JournalExperimental cell research
Volume121
Issue number1
DOIs
StatePublished - Jun 1979

ASJC Scopus subject areas

  • Cell Biology

Fingerprint

Dive into the research topics of 'Effects of temperature on glycosyltransferase activity in the plasma membrane of L cells'. Together they form a unique fingerprint.

Cite this