Effects of small intravenous doses of epinephrine on serum insulin, glucose tolerance and serum free fatty acids

P. V. Cardon, J. L. Weiss, P. S. Mueller

Research output: Contribution to journalArticle

Abstract

Eighteen intravenous glucose tolerance tests (IVGTT) were carried out in 6 young, normal subjects while they were receiving normal saline or epinephrine (E) intravenously at the low rates of 0.1 and 0.3 μgm. per minute. The lower dose of E caused changes in the rate of urinary excretion of free E similar to those caused by caffeine; the higher dose caused changes similar to those reported to occur during various moderate to severe stress. The higher dose of E augmented the insulin response to IVGTT. Glucose tolerance was not significantly decreased, resulting in relatively low glucose insulin ratios following glucose injection. Serum free fatty acids were unaffected.

Original languageEnglish (US)
Pages (from-to)743-747
Number of pages5
JournalDiabetes
Volume23
Issue number9
DOIs
StatePublished - Jan 1 1974
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

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