Effects of Reward Timing Information on Cue Associability Are Mediated by Amygdala Central Nucleus

Daniel S. Wheeler, Peter C. Holland

Research output: Contribution to journalArticle

Abstract

The central nucleus of the amygdala (CeA) has been implicated in a range of associative learning phenomena often attributed to changes in attentional processing of events. Experiments using a number of behavioral tasks have shown that rats with lesions of CeA fail to show the enhancements of stimulus associability that are normally induced by the surprising omission of expected events. By contrast, in other tasks, rats with lesions of CeA show normal enhancements of associability when events are presented unexpectedly. In this experiment, we examined the effects of CeA lesions on changes in cue associability in a reward timing task. In sham-lesioned rats, the associability of cues that were followed by stimuli that provided reward timing information was maintained at higher levels than that of cues that were followed by uninformative stimuli. Rats with lesions of CeA failed to show this advantage. These results indicate that the role of CeA in the modulation of associability is not limited to cases of event omission.

Original languageEnglish (US)
Pages (from-to)46-53
Number of pages8
JournalBehavioral Neuroscience
Volume125
Issue number1
DOIs
StatePublished - Feb 1 2011

Keywords

  • Amygdala
  • Associability
  • Attention
  • Information
  • Pearce-Hall model
  • Reward timing

ASJC Scopus subject areas

  • Behavioral Neuroscience

Fingerprint Dive into the research topics of 'Effects of Reward Timing Information on Cue Associability Are Mediated by Amygdala Central Nucleus'. Together they form a unique fingerprint.

  • Cite this