Effects of respiratory and non-respiratory factors on disability among older adults with airway obstruction: The Cardiovascular Health Study

Emily Locke, Stephen Thielke, Paula Diehr, Anthony G. Wilsdon, R. Graham Barr, Nadia Hansel, Vishesh K. Kapur, Jerry Krishnan, Paul Enright, Susan R. Heckbert, Richard A. Kronmal, Vincent S. Fan

Research output: Contribution to journalArticle

Abstract

Background: High rates of disability associated with chronic airway obstruction may be caused by impaired pulmonary function, pulmonary symptoms, other chronic diseases, or systemic inflammation. Methods: We analyzed data from the Cardiovascular Health Study, a longitudinal cohort of 5888 older adults. Categories of lung function (normal; restricted; borderline, mild-moderate, and severe obstruction) were delineated by baseline spirometry (without bronchodilator). Disability-free years were calculated as total years alive a

Original languageEnglish (US)
Pages (from-to)588-596
Number of pages9
JournalCOPD: Journal of Chronic Obstructive Pulmonary Disease
Volume10
Issue number5
DOIs
StatePublished - Oct 1 2013

Keywords

  • Chronic airfl ow obstruction
  • disability
  • disablement process
  • instrumental activities of daily living

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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    Locke, E., Thielke, S., Diehr, P., Wilsdon, A. G., Graham Barr, R., Hansel, N., Kapur, V. K., Krishnan, J., Enright, P., Heckbert, S. R., Kronmal, R. A., & Fan, V. S. (2013). Effects of respiratory and non-respiratory factors on disability among older adults with airway obstruction: The Cardiovascular Health Study. COPD: Journal of Chronic Obstructive Pulmonary Disease, 10(5), 588-596. https://doi.org/10.3109/15412555.2013.781148