BACKGROUND: Intestinal electrical stimulation (IES) with long pulses has been reported to inhibit motility as well as accelerate transit of continuous infusion. However, it is unknown whether there is a correlation between the IES-induced alterations in motility and transit and whether there is a difference in transit during IES between continuous infusion and bolus infusion.
METHODS: The study was performed in 2 postprandial sessions (control and stimulation) in dogs with 2 pairs of serosal electrodes and 2 intestinal cannulas. Intestinal motility and transit with and without IES were measured by manometry and phenol red, respectively.
RESULTS: IES significantly decreased intestinal motility and increased transit time. There was a significant correlation between motility index and transit during IES.
CONCLUSIONS: IES inhibits both intestinal bolus motility and transit. There is correlation between motility and transit during IES.
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