Effects of infant sex on mother-to-child transmission of HIV-1 according to timing of infection in Zimbabwe

Ellen G. Piwoz, Jean H. Humphrey, Edmore T. Marinda, Kuda Mutasa, Lawrence H. Moulton, Peter J. Iliff

Research output: Contribution to journalArticlepeer-review

Abstract

We examined the relationship between sex and the risk of intrauterine, intrapartum and postnatal HIV transmission among 4495 infants born to HIV-infected mothers in Harare, Zimbabwe. Intrauterine transmission was 8.6%, and consistent with other studies was higher among girl than boy infants (AOR 1.53; 95% CI 1.23-1.91). Unlike previous studies, we observed no independent effect of infant sex on intrapartum or breastfeeding-associated HIV transmission. Sex-specific postnatal prevention strategies are not warranted in this population.

Original languageEnglish (US)
Pages (from-to)1981-1984
Number of pages4
JournalAIDS
Volume20
Issue number15
DOIs
StatePublished - Oct 1 2006

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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