Effects of induced oxygen want in patients with cardiac pain

Robert L. Levy, Alvan L. Barach, Howard G. Bruenn

Research output: Contribution to journalArticle

Abstract

1. 1. An apparatus has been described for inducing systemic oxygen want in patients, without rebreathing. 2. 2. Observations were made on 37 patients with cardiac disease and on 11 with normal hearts. A level of oxygen saturation was reached ranging from 67 to 83 per cent, as determined in samples of arterial blood. 3. 3. There was no constant relationship between the occurrence of cardiac pain and changes in heart rate, respiratory rate, blood pressure, venous pressure, circulation time and the degree of arterial unsaturation. 4. 4. Pain occurred inconstantly in repeated tests, except in two patients with aortic stenosis and in one with advanced coronary lesions. In the two patients with aortic stenosis there was no compensatory shortening of the circulation time during the anoxemic period. 5. 5. Untoward effects were observed in two patients with healed infarcts of the heart. Both recovered promptly. The bearing of these experiences on the danger of aeroplane flights for persons with disease of the coronary arteries was discussed. 6. 6. Oxygen want is an important, and apparently the determining factor in the causation of cardiac pain. It is most effective when the coronary blood flow is reduced. Ischemia and anoxemia complement each other as pain-inducing agents in the heart. Other variable circumstances are also concerned. 7. 7. The induction of systemic oxygen want may prove to be useful as a test for coronary insufficiency; it is not recommended for general use at this time.

Original languageEnglish (US)
Pages (from-to)187-200
Number of pages14
JournalAmerican Heart Journal
Volume15
Issue number2
StatePublished - Feb 1938
Externally publishedYes

Fingerprint

Oxygen
Pain
Aortic Valve Stenosis
Venous Pressure
Respiratory Rate
Causality
Coronary Artery Disease
Heart Diseases
Ischemia
Heart Rate
Blood Pressure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Levy, R. L., Barach, A. L., & Bruenn, H. G. (1938). Effects of induced oxygen want in patients with cardiac pain. American Heart Journal, 15(2), 187-200.

Effects of induced oxygen want in patients with cardiac pain. / Levy, Robert L.; Barach, Alvan L.; Bruenn, Howard G.

In: American Heart Journal, Vol. 15, No. 2, 02.1938, p. 187-200.

Research output: Contribution to journalArticle

Levy, RL, Barach, AL & Bruenn, HG 1938, 'Effects of induced oxygen want in patients with cardiac pain', American Heart Journal, vol. 15, no. 2, pp. 187-200.
Levy RL, Barach AL, Bruenn HG. Effects of induced oxygen want in patients with cardiac pain. American Heart Journal. 1938 Feb;15(2):187-200.
Levy, Robert L. ; Barach, Alvan L. ; Bruenn, Howard G. / Effects of induced oxygen want in patients with cardiac pain. In: American Heart Journal. 1938 ; Vol. 15, No. 2. pp. 187-200.
@article{e45b20c1f27a453385a3b0f8a6657141,
title = "Effects of induced oxygen want in patients with cardiac pain",
abstract = "1. 1. An apparatus has been described for inducing systemic oxygen want in patients, without rebreathing. 2. 2. Observations were made on 37 patients with cardiac disease and on 11 with normal hearts. A level of oxygen saturation was reached ranging from 67 to 83 per cent, as determined in samples of arterial blood. 3. 3. There was no constant relationship between the occurrence of cardiac pain and changes in heart rate, respiratory rate, blood pressure, venous pressure, circulation time and the degree of arterial unsaturation. 4. 4. Pain occurred inconstantly in repeated tests, except in two patients with aortic stenosis and in one with advanced coronary lesions. In the two patients with aortic stenosis there was no compensatory shortening of the circulation time during the anoxemic period. 5. 5. Untoward effects were observed in two patients with healed infarcts of the heart. Both recovered promptly. The bearing of these experiences on the danger of aeroplane flights for persons with disease of the coronary arteries was discussed. 6. 6. Oxygen want is an important, and apparently the determining factor in the causation of cardiac pain. It is most effective when the coronary blood flow is reduced. Ischemia and anoxemia complement each other as pain-inducing agents in the heart. Other variable circumstances are also concerned. 7. 7. The induction of systemic oxygen want may prove to be useful as a test for coronary insufficiency; it is not recommended for general use at this time.",
author = "Levy, {Robert L.} and Barach, {Alvan L.} and Bruenn, {Howard G.}",
year = "1938",
month = "2",
language = "English (US)",
volume = "15",
pages = "187--200",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
number = "2",

}

TY - JOUR

T1 - Effects of induced oxygen want in patients with cardiac pain

AU - Levy, Robert L.

AU - Barach, Alvan L.

AU - Bruenn, Howard G.

PY - 1938/2

Y1 - 1938/2

N2 - 1. 1. An apparatus has been described for inducing systemic oxygen want in patients, without rebreathing. 2. 2. Observations were made on 37 patients with cardiac disease and on 11 with normal hearts. A level of oxygen saturation was reached ranging from 67 to 83 per cent, as determined in samples of arterial blood. 3. 3. There was no constant relationship between the occurrence of cardiac pain and changes in heart rate, respiratory rate, blood pressure, venous pressure, circulation time and the degree of arterial unsaturation. 4. 4. Pain occurred inconstantly in repeated tests, except in two patients with aortic stenosis and in one with advanced coronary lesions. In the two patients with aortic stenosis there was no compensatory shortening of the circulation time during the anoxemic period. 5. 5. Untoward effects were observed in two patients with healed infarcts of the heart. Both recovered promptly. The bearing of these experiences on the danger of aeroplane flights for persons with disease of the coronary arteries was discussed. 6. 6. Oxygen want is an important, and apparently the determining factor in the causation of cardiac pain. It is most effective when the coronary blood flow is reduced. Ischemia and anoxemia complement each other as pain-inducing agents in the heart. Other variable circumstances are also concerned. 7. 7. The induction of systemic oxygen want may prove to be useful as a test for coronary insufficiency; it is not recommended for general use at this time.

AB - 1. 1. An apparatus has been described for inducing systemic oxygen want in patients, without rebreathing. 2. 2. Observations were made on 37 patients with cardiac disease and on 11 with normal hearts. A level of oxygen saturation was reached ranging from 67 to 83 per cent, as determined in samples of arterial blood. 3. 3. There was no constant relationship between the occurrence of cardiac pain and changes in heart rate, respiratory rate, blood pressure, venous pressure, circulation time and the degree of arterial unsaturation. 4. 4. Pain occurred inconstantly in repeated tests, except in two patients with aortic stenosis and in one with advanced coronary lesions. In the two patients with aortic stenosis there was no compensatory shortening of the circulation time during the anoxemic period. 5. 5. Untoward effects were observed in two patients with healed infarcts of the heart. Both recovered promptly. The bearing of these experiences on the danger of aeroplane flights for persons with disease of the coronary arteries was discussed. 6. 6. Oxygen want is an important, and apparently the determining factor in the causation of cardiac pain. It is most effective when the coronary blood flow is reduced. Ischemia and anoxemia complement each other as pain-inducing agents in the heart. Other variable circumstances are also concerned. 7. 7. The induction of systemic oxygen want may prove to be useful as a test for coronary insufficiency; it is not recommended for general use at this time.

UR - http://www.scopus.com/inward/record.url?scp=9244255993&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=9244255993&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:9244255993

VL - 15

SP - 187

EP - 200

JO - American Heart Journal

JF - American Heart Journal

SN - 0002-8703

IS - 2

ER -