Effects of fusidic acid on staphylococcal keratitis

Khalid F. Tabbara, Sobhi Antonios, Henry Alvarez

Research output: Contribution to journalArticle

Abstract

We treated 20 consecutive patients suffering from staphylococcal keratitis with topical fusidic acid 1% suspension in a carbomer gel. Fifteen (79%) of the isolated Staphylococcus epidermidis strains were resistant to methicillin, but all were sensitive to fusidic acid by in-vitro testing. The keratitis showed evidence of healing in 17 (85%) of the 20 patients. The healing times ranged between 5 and 21 days (mean 10.5 days). In this open clinical trial fusidic acid proved to be a safe and effective antibiotic for the treatment of staphylococcal keratitis.

Original languageEnglish (US)
Pages (from-to)136-139
Number of pages4
JournalBritish Journal of Ophthalmology
Volume73
Issue number2
DOIs
Publication statusPublished - 1989
Externally publishedYes

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ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Emergency Medicine
  • Ophthalmology

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