Effects of esophageal stimulation in patients with functional disorders of the gastrointestinal tract

Markad V. Kamath, Andrew May, Stephan Hollerbach, Robert Bulat, Gervais Tougas, Ernest L. Fallen, Glen Shine, Adrian R. Upton

Research output: Contribution to journalArticlepeer-review

Abstract

The esophagus in patients with diabetic neuropathy and with non-cardiac chest pain (NCCP) was stimulated through brief electrical pulses and recording the responses in the form of cortical evoked potentials (EPs) and PS/HRV. An odd-ball paradigm was set up to generate cognitive responses on the scalp, generally called P300 evoked potentials. The results suggest that patients with NCCP have a diminished perception threshold and the increased perception results in an exaggerated brainstem response and altered cortical processing of visceral sensations. The patients also showed an increased vagal power.

Original languageEnglish (US)
Pages (from-to)308-309
Number of pages2
JournalCritical reviews in biomedical engineering
Volume26
Issue number5
StatePublished - Dec 1 1998
Externally publishedYes

ASJC Scopus subject areas

  • Biomedical Engineering

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