Effects of enhanced viscosity on canine gastric and intestinal motility

Xiaohong Xu, Doug Brining, Asad Rafiq, James Hayes, J. D Z Chen, Jiande Chen

Research output: Contribution to journalArticle

Abstract

Background and Aim: The aim of this study was to investigate the effect of enhanced viscosity on gastric emptying and gastrointestinal motor and myoelectrical activities in dogs. Method: The study was performed in eight healthy female hound dogs chronically implanted with four pairs of gastric and two pairs of intestinal serosal electrodes and a duodenal fistula. Each dog was studied in three sessions and fed with three test meals with different viscosity. Gastric emptying was monitored for 2 h simultaneously with gastric and intestinal myoelectrical recordings. Results: The liquid test meal containing either 0.78% or 1.21% of galactomannan significantly delayed gastric emptying but had no effect on postprandial blood glucose levels in comparison with the meal containing no galactomannan. The liquid test meal containing either 0.78% or 1.21% of galactomannan significantly increased the frequency and strength of intestinal motility but had no effect on intestinal slow wave rhythms. The product with enhanced viscosity had no effect on gastric motor activity or gastric slow waves. Conclusion: It was concluded that enhanced viscosity delays gastric emptying, increases postprandial intestinal but not gastric motility, and has no effects on gastric or intestinal slow waves.

Original languageEnglish (US)
Pages (from-to)387-394
Number of pages8
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume20
Issue number3
DOIs
StatePublished - 2005
Externally publishedYes

Fingerprint

Gastrointestinal Motility
Viscosity
Canidae
Stomach
Gastric Emptying
Meals
Dogs
Motor Activity
Fistula
Blood Glucose
Electrodes
galactomannan

Keywords

  • Blood glucose
  • Electrogastrography
  • Gastric emptying
  • Gastrointestinal motility
  • Gastrointestinal myoelectrical activity

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Effects of enhanced viscosity on canine gastric and intestinal motility. / Xu, Xiaohong; Brining, Doug; Rafiq, Asad; Hayes, James; Chen, J. D Z; Chen, Jiande.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 20, No. 3, 2005, p. 387-394.

Research output: Contribution to journalArticle

Xu, Xiaohong ; Brining, Doug ; Rafiq, Asad ; Hayes, James ; Chen, J. D Z ; Chen, Jiande. / Effects of enhanced viscosity on canine gastric and intestinal motility. In: Journal of Gastroenterology and Hepatology (Australia). 2005 ; Vol. 20, No. 3. pp. 387-394.
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