Abstract
In this study, we compared the effects of BPA-PP with that of polyurethane (PU), a suspected toxin and a widely used biodegradable polymer (polylactic acid, PLA). The macrophage cell culture model for evaluating biocompatibility can effectively screen polymer candidates for drug delivery systems. PLA (Polyacetic Acid) (a polymer successfully used in this application) and BPA-PP did not affect macrophage DNA synthesis, protein synthesis, or interleukin-1 production. However, PU was found to be cytotoxic and impaired macrophage functional ability.
| Original language | English (US) |
|---|---|
| Pages | 182 |
| Number of pages | 1 |
| State | Published - 1991 |
| Externally published | Yes |
| Event | 17th Annual Meeting of the Society for Biomaterials in conjunction with the 23rd International Biomaterials Symposium - Scottsdale, AZ, USA Duration: May 1 1991 → May 5 1991 |
Other
| Other | 17th Annual Meeting of the Society for Biomaterials in conjunction with the 23rd International Biomaterials Symposium |
|---|---|
| City | Scottsdale, AZ, USA |
| Period | 5/1/91 → 5/5/91 |
ASJC Scopus subject areas
- General Materials Science