TY - JOUR
T1 - Effects of aging on the diurnal pattern of water intake in rats
AU - Burwell, Rebecca D.
AU - Whealin, Julia
AU - Gallagher, Michela
PY - 1992/11
Y1 - 1992/11
N2 - This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.
AB - This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.
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U2 - 10.1016/0163-1047(92)90468-J
DO - 10.1016/0163-1047(92)90468-J
M3 - Article
C2 - 1456941
AN - SCOPUS:0027052873
VL - 58
SP - 196
EP - 203
JO - Neurobiology of Learning and Memory
JF - Neurobiology of Learning and Memory
SN - 1074-7427
IS - 3
ER -