Abstract
This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 196-203 |
| Number of pages | 8 |
| Journal | Behavioral and Neural Biology |
| Volume | 58 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1992 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Physiology
Cite this
Effects of aging on the diurnal pattern of water intake in rats. / Burwell, Rebecca D.; Whealin, Julia; Gallagher, Michela.
In: Behavioral and Neural Biology, Vol. 58, No. 3, 1992, p. 196-203.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of aging on the diurnal pattern of water intake in rats
AU - Burwell, Rebecca D.
AU - Whealin, Julia
AU - Gallagher, Michela
PY - 1992
Y1 - 1992
N2 - This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.
AB - This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.
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UR - http://www.scopus.com/inward/citedby.url?scp=0027052873&partnerID=8YFLogxK
U2 - 10.1016/0163-1047(92)90468-J
DO - 10.1016/0163-1047(92)90468-J
M3 - Article
VL - 58
SP - 196
EP - 203
JO - Neurobiology of Learning and Memory
JF - Neurobiology of Learning and Memory
SN - 1074-7427
IS - 3
ER -