Abstract
Objective: High prevalences of vitamin A deficiency and anaemia among adolescents warrant interventions. This study evaluated the effectiveness of school-based supplementation to reduce anaemia and improve vitamin A status. Design: School-based, grade-randomized, intervention. Subjects and setting: In all, 1757 girls and 1859 boys, aged 12-15 y, in 24 Junior High Schools. Interventions: Weekly supplementation for 14 weeks with 60 mg iron and 250 μg folate (Fe group; n = 978), 10 000 IU vitamin A (VA group; n = 970) or both (VAFe group; n = 1042) to subjects in 15 schools, compared to subjects in nine other schools not receiving supplements (control; n = 626). Results: The baseline anaemia prevalence (Hb <120 g/l) in girls was 20% (prepubertal) and 26% (pubertal), and in boys 24% (pre-pubertal) and 11% (pubertal). Serum retinol concentrations were low (<1.05 μ mol/l) in 41% of boys and 45% of girls. The interventions did not increase haemoglobin concentrations. Serum retinol concentration of boys, but not girls, in the VA group increased (0.33 vs 0.07 μmol/l in controls; P
| Original language | English (US) |
|---|---|
| Pages (from-to) | 927-937 |
| Number of pages | 11 |
| Journal | European Journal of Clinical Nutrition |
| Volume | 58 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2004 |
| Externally published | Yes |
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Keywords
- Adolescents
- Anaemia
- Indonesia
- Vitamin A deficiency
- Weekly supplementation
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Food Science
Cite this
Effectiveness of weekly vitamin A (10 000 IU) and iron (60 mg) supplementation for adolescent boys and girls through schools in rural and urban East Java, Indonesia. / Soekarjo, D. D.; de Pee, S.; Kusin, J. A.; Schreurs, W. H P; Schultink, W.; Muhilal, A.; Bloem, Martin.
In: European Journal of Clinical Nutrition, Vol. 58, No. 6, 06.2004, p. 927-937.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effectiveness of weekly vitamin A (10 000 IU) and iron (60 mg) supplementation for adolescent boys and girls through schools in rural and urban East Java, Indonesia
AU - Soekarjo, D. D.
AU - de Pee, S.
AU - Kusin, J. A.
AU - Schreurs, W. H P
AU - Schultink, W.
AU - Muhilal, A.
AU - Bloem, Martin
PY - 2004/6
Y1 - 2004/6
N2 - Objective: High prevalences of vitamin A deficiency and anaemia among adolescents warrant interventions. This study evaluated the effectiveness of school-based supplementation to reduce anaemia and improve vitamin A status. Design: School-based, grade-randomized, intervention. Subjects and setting: In all, 1757 girls and 1859 boys, aged 12-15 y, in 24 Junior High Schools. Interventions: Weekly supplementation for 14 weeks with 60 mg iron and 250 μg folate (Fe group; n = 978), 10 000 IU vitamin A (VA group; n = 970) or both (VAFe group; n = 1042) to subjects in 15 schools, compared to subjects in nine other schools not receiving supplements (control; n = 626). Results: The baseline anaemia prevalence (Hb <120 g/l) in girls was 20% (prepubertal) and 26% (pubertal), and in boys 24% (pre-pubertal) and 11% (pubertal). Serum retinol concentrations were low (<1.05 μ mol/l) in 41% of boys and 45% of girls. The interventions did not increase haemoglobin concentrations. Serum retinol concentration of boys, but not girls, in the VA group increased (0.33 vs 0.07 μmol/l in controls; P
AB - Objective: High prevalences of vitamin A deficiency and anaemia among adolescents warrant interventions. This study evaluated the effectiveness of school-based supplementation to reduce anaemia and improve vitamin A status. Design: School-based, grade-randomized, intervention. Subjects and setting: In all, 1757 girls and 1859 boys, aged 12-15 y, in 24 Junior High Schools. Interventions: Weekly supplementation for 14 weeks with 60 mg iron and 250 μg folate (Fe group; n = 978), 10 000 IU vitamin A (VA group; n = 970) or both (VAFe group; n = 1042) to subjects in 15 schools, compared to subjects in nine other schools not receiving supplements (control; n = 626). Results: The baseline anaemia prevalence (Hb <120 g/l) in girls was 20% (prepubertal) and 26% (pubertal), and in boys 24% (pre-pubertal) and 11% (pubertal). Serum retinol concentrations were low (<1.05 μ mol/l) in 41% of boys and 45% of girls. The interventions did not increase haemoglobin concentrations. Serum retinol concentration of boys, but not girls, in the VA group increased (0.33 vs 0.07 μmol/l in controls; P
KW - Adolescents
KW - Anaemia
KW - Indonesia
KW - Vitamin A deficiency
KW - Weekly supplementation
UR - http://www.scopus.com/inward/record.url?scp=3142673449&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=3142673449&partnerID=8YFLogxK
U2 - 10.1038/sj.ejcn.1601914
DO - 10.1038/sj.ejcn.1601914
M3 - Article
C2 - 15164114
AN - SCOPUS:3142673449
VL - 58
SP - 927
EP - 937
JO - European Journal of Clinical Nutrition
JF - European Journal of Clinical Nutrition
SN - 0954-3007
IS - 6
ER -