Analysis of treatment response among HIV-infected children in India on first-line antiretroviral treatment for >2 years revealed that 85% were virologically suppressed. Of those with virologie failure, only 17% manifested immunologic failure, whereas majority had resistance-associated mutations. The presence of resistance highlights the need for virologie monitoring of children receiving antiretroviral treatment to optimize treatment success and preserve future treatment options.
- Drug resistance
- Pediatric antiretroviral treatment
- Virological failure
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Microbiology (medical)
- Infectious Diseases