Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa

Catherine Sutcliffe, Janneke H. van Dijk, Carolyn Bolton, Deborah Persaud, William J Moss

Research output: Contribution to journalArticle

Abstract

Assessment of antiretroviral treatment programmes for HIV-infected children in sub-Saharan Africa is important to enable the development of effective care and improve treatment outcomes. We review the effectiveness of paediatric antiretroviral treatment programmes in sub-Saharan Africa and discuss the implications of these findings for the care and treatment of HIV-infected children in this region. Available reports indicate that programmes in sub-Saharan Africa achieve treatment outcomes similar to those in North America and Europe. However, progress in several areas is required to improve the care of HIV-infected children in sub-Saharan Africa. The findings emphasise the need for low-cost diagnostic tests that allow for earlier identification of HIV infection in infants living in sub-Saharan Africa, improved access to antiretroviral treatment programmes, including expansion of care into rural areas, and the integration of antiretroviral treatment programmes with other health-care services, such as nutritional support.

Original languageEnglish (US)
Pages (from-to)477-489
Number of pages13
JournalLancet Infectious Diseases
Volume8
Issue number8
DOIs
StatePublished - Aug 2008

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Africa South of the Sahara
HIV
Therapeutics
Nutritional Support
North America
Routine Diagnostic Tests
Health Services
HIV Infections
Pediatrics
Delivery of Health Care
Costs and Cost Analysis

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa. / Sutcliffe, Catherine; van Dijk, Janneke H.; Bolton, Carolyn; Persaud, Deborah; Moss, William J.

In: Lancet Infectious Diseases, Vol. 8, No. 8, 08.2008, p. 477-489.

Research output: Contribution to journalArticle

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