TY - JOUR
T1 - Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa
AU - Sutcliffe, Catherine G.
AU - van Dijk, Janneke H.
AU - Bolton, Carolyn
AU - Persaud, Deborah
AU - Moss, William J.
PY - 2008/8
Y1 - 2008/8
N2 - Assessment of antiretroviral treatment programmes for HIV-infected children in sub-Saharan Africa is important to enable the development of effective care and improve treatment outcomes. We review the effectiveness of paediatric antiretroviral treatment programmes in sub-Saharan Africa and discuss the implications of these findings for the care and treatment of HIV-infected children in this region. Available reports indicate that programmes in sub-Saharan Africa achieve treatment outcomes similar to those in North America and Europe. However, progress in several areas is required to improve the care of HIV-infected children in sub-Saharan Africa. The findings emphasise the need for low-cost diagnostic tests that allow for earlier identification of HIV infection in infants living in sub-Saharan Africa, improved access to antiretroviral treatment programmes, including expansion of care into rural areas, and the integration of antiretroviral treatment programmes with other health-care services, such as nutritional support.
AB - Assessment of antiretroviral treatment programmes for HIV-infected children in sub-Saharan Africa is important to enable the development of effective care and improve treatment outcomes. We review the effectiveness of paediatric antiretroviral treatment programmes in sub-Saharan Africa and discuss the implications of these findings for the care and treatment of HIV-infected children in this region. Available reports indicate that programmes in sub-Saharan Africa achieve treatment outcomes similar to those in North America and Europe. However, progress in several areas is required to improve the care of HIV-infected children in sub-Saharan Africa. The findings emphasise the need for low-cost diagnostic tests that allow for earlier identification of HIV infection in infants living in sub-Saharan Africa, improved access to antiretroviral treatment programmes, including expansion of care into rural areas, and the integration of antiretroviral treatment programmes with other health-care services, such as nutritional support.
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U2 - 10.1016/S1473-3099(08)70180-4
DO - 10.1016/S1473-3099(08)70180-4
M3 - Review article
C2 - 18652994
AN - SCOPUS:47549096477
SN - 1473-3099
VL - 8
SP - 477
EP - 489
JO - The Lancet Infectious Diseases
JF - The Lancet Infectious Diseases
IS - 8
ER -