Effect of truncated projections on defect detection in attenuation- compensated fanbeam cardiac SPECT

George K. Gregoriou, Benjamin Tsui, Grant T. Gullberg

Research output: Contribution to journalArticle

Abstract

For some camera systems used in cardiac SPECT, the limited field of view of fanbeam-collimated detectors produces truncation in the projection data. This truncation may generate artifacts and distortions in the transmission CT images and in the attenuation-corrected myocardial SPECT images (that use the transmission CT images as attenuation maps), thus affecting clinical diagnosis. Concern over this problem stimulated us to evaluate the effect of truncation with human observer performance studies. Methods: A three- dimensional mathematical cardiac-torso phantom that realistically models the attenuation and 201TI uptake distributions in different organs of the upper torso was used for the investigation. Five degrees of truncation (from 0% to 40% truncation) in the projection data were simulated by the use of five different detector sizes collimated by fanbeam collimators. The attenuation maps were obtained by reconstructing the truncated transmission data generated from these fanbeam geometries. The emission data obtained with the same fanbeam geometries were reconstructed by using the maximum likelihood-expectation maximization algorithm and were corrected for attenuation using the reconstructed attenuation maps. Two observer performance studies were performed. In Study 1, the images were reconstructed without using the body contour as support, whereas in Study 2, the exact body contour was used in reconstructing both the attenuation maps and the attenuation-corrected SPECT images. Results: The results of the receiver operating characteristics analysis indicate that there is very little difference between detection for the various degrees of truncation, and this difference only becomes noticeable for severe truncation of greater than 40%. Conclusion: Using the acquisition and processing methods, we found the use of the body contour as support in reconstructing truncated transmission CT and SPECT data reduces the loss of defect detectability in attenuation- compensated myocardial SPECT images due to truncated data.

Original languageEnglish (US)
Pages (from-to)166-175
Number of pages10
JournalJournal of Nuclear Medicine
Volume39
Issue number1
StatePublished - Jan 1998
Externally publishedYes

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Single-Photon Emission-Computed Tomography
Torso
ROC Curve
Artifacts

Keywords

  • Fanbeam myocardial SPECT
  • Observer performance study
  • Receiver operating characteristics study
  • Truncated projection

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Effect of truncated projections on defect detection in attenuation- compensated fanbeam cardiac SPECT. / Gregoriou, George K.; Tsui, Benjamin; Gullberg, Grant T.

In: Journal of Nuclear Medicine, Vol. 39, No. 1, 01.1998, p. 166-175.

Research output: Contribution to journalArticle

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