Einfluss des Konservierungsmittels Thiomersal auf die Interleukin-1 Beta Ausschüttung humaner peripherer Blutzellen.

Translated title of the contribution: Effect of the preservative thiomersal on the release of interleukin-1 beta from human peripheral blood cells

M. Fischer, B. Keller-Stanislawski, S. Schober-Bendixen, R. Schosser, K. Hacke, T. Hartung, T. Montag

Research output: Contribution to journalArticle

Abstract

Several vaccines have been tested in the human whole blood pyrogen test as an alternative to the rabbit pyrogen test. As reported previously by our group, the alternative test system is basically applicable to vaccines. The widely used conservative thiomersal is influencing the test system. Surprisingly, the induction of fever inducing cytokines by endotoxin contaminations and other pyrogens can be suppressed by thiomersal.

Translated title of the contributionEffect of the preservative thiomersal on the release of interleukin-1 beta from human peripheral blood cells
Original languageGerman
Pages (from-to)47-49
Number of pages3
JournalALTEX : Alternativen zu Tierexperimenten
Volume18
Issue number1
StatePublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Medical Laboratory Technology

Fingerprint Dive into the research topics of 'Effect of the preservative thiomersal on the release of interleukin-1 beta from human peripheral blood cells'. Together they form a unique fingerprint.

  • Cite this

    Fischer, M., Keller-Stanislawski, B., Schober-Bendixen, S., Schosser, R., Hacke, K., Hartung, T., & Montag, T. (2001). Einfluss des Konservierungsmittels Thiomersal auf die Interleukin-1 Beta Ausschüttung humaner peripherer Blutzellen. ALTEX : Alternativen zu Tierexperimenten, 18(1), 47-49.