Effect of stimulus intensity on short latency somatosensory evoked potentials

Ronald P. Lesser, Ruth Koehle, Hans Lueders

Research output: Contribution to journalArticlepeer-review


The peripheral and central potentials evoked by percutaneous electrical stimulation of the median nerve were investigated in a group of neurologically normal subjects. We found: 1. (1) Motor threshold stimulation gave consistently submaximal responses and probably does not represent an optimal intensity for routine use. 2. (2) The sum of motor plus sensory threshold gave potentials which were consistently at, or close to, maximal in amplitude. This intensity was comfortable for all subjects. 3. (3) When stimulating at intensities above motor threshold, the increase in amplitude of peripheral potentials markedly exceeded that of the central potentials. There was evidence suggesting that amplitudes would decline at very high stumulus intensities. 4. (4) The P13 peak latency and the P13-N9 interpeak latency declined and the N18-P13 interpeak latency increased with increasing intensities of stimulation. The N9 and N18 peak latencies remained stable.

Original languageEnglish (US)
Pages (from-to)377-382
Number of pages6
JournalElectroencephalography and Clinical Neurophysiology
Issue number3
StatePublished - Sep 1979
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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