Effect of steroid hormones on arachidonic acid metabolites of endothelial cells

Frank R. Witter, Maria C. DiBlasi

Research output: Contribution to journalArticle

Abstract

The effect of estrogen, progesterone, testosterone, and hydrocortisone on prostacyclin, thromboxane, prostaglandin E, and prostaglandin F from cultured endothelial cells was investigated. No effect was found on prostacyclin, prostaglandin E, and prostaglandin F. Estrogen increased the release of thromboxane. The significance of this finding with regard to venous thrombolic events associated with estrogen use is discussed.

Original languageEnglish (US)
Pages (from-to)747-751
Number of pages5
JournalObstetrics and gynecology
Volume63
Issue number5
StatePublished - May 1984

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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