TY - JOUR
T1 - Effect of specific non-pharmaceutical intervention policies on SARS-CoV-2 transmission in the counties of the United States
AU - UFCOVID Interventions Team
AU - Yang, Bingyi
AU - Huang, Angkana T.
AU - Garcia-Carreras, Bernardo
AU - Hart, William E.
AU - Staid, Andrea
AU - Hitchings, Matt D.T.
AU - Lee, Elizabeth C.
AU - Howe, Chanelle J.
AU - Grantz, Kyra H.
AU - Wesolowksi, Amy
AU - Lemaitre, Joseph Chadi
AU - Rattigan, Susan
AU - Moreno, Carlos
AU - Borgert, Brooke A.
AU - Dale, Celeste
AU - Quigley, Nicole
AU - Cummings, Andrew
AU - McLorg, Alizée
AU - LoMonaco, Kaelene
AU - Schlossberg, Sarah
AU - Barron-Kraus, Drew
AU - Shrock, Harrison
AU - Khoury, Stephanie
AU - Indra, Meenal
AU - Yau, Hung Leong
AU - Cummings, Ben
AU - Giannas, Peter
AU - McLean, Martha Grace
AU - Hubbard, Ken
AU - Saunders, Camazia
AU - Weldon, Caroline
AU - Phillips, Caroline
AU - Rosenbaum, David
AU - Tabla, Dianelys
AU - Lessler, Justin
AU - Laird, Carl D.
AU - Cummings, Derek A.T.
N1 - Publisher Copyright:
© 2021, The Author(s).
PY - 2021/12/1
Y1 - 2021/12/1
N2 - Non-pharmaceutical interventions (NPIs) remain the only widely available tool for controlling the ongoing SARS-CoV-2 pandemic. We estimated weekly values of the effective basic reproductive number (Reff) using a mechanistic metapopulation model and associated these with county-level characteristics and NPIs in the United States (US). Interventions that included school and leisure activities closure and nursing home visiting bans were all associated with a median Reff below 1 when combined with either stay at home orders (median Reff 0.97, 95% confidence interval (CI) 0.58–1.39) or face masks (median Reff 0.97, 95% CI 0.58–1.39). While direct causal effects of interventions remain unclear, our results suggest that relaxation of some NPIs will need to be counterbalanced by continuation and/or implementation of others.
AB - Non-pharmaceutical interventions (NPIs) remain the only widely available tool for controlling the ongoing SARS-CoV-2 pandemic. We estimated weekly values of the effective basic reproductive number (Reff) using a mechanistic metapopulation model and associated these with county-level characteristics and NPIs in the United States (US). Interventions that included school and leisure activities closure and nursing home visiting bans were all associated with a median Reff below 1 when combined with either stay at home orders (median Reff 0.97, 95% confidence interval (CI) 0.58–1.39) or face masks (median Reff 0.97, 95% CI 0.58–1.39). While direct causal effects of interventions remain unclear, our results suggest that relaxation of some NPIs will need to be counterbalanced by continuation and/or implementation of others.
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U2 - 10.1038/s41467-021-23865-8
DO - 10.1038/s41467-021-23865-8
M3 - Article
C2 - 34117244
AN - SCOPUS:85107809637
SN - 2041-1723
VL - 12
JO - Nature communications
JF - Nature communications
IS - 1
M1 - 3560
ER -