Effect of secondhand smoke on asthma control among black and Latino children

Sam S. Oh, Haig Tcheurekdjian, Lindsey A. Roth, Elizabeth A. Nguyen, Saunak Sen, Joshua M. Galanter, Adam Davis, Harold J. Farber, Frank D. Gilliland, Rajesh Kumar, Pedro C. Avila, Emerita Brigino-Buenaventura, Rocio Chapela, Jean G. Ford, Michael A. Lenoir, Fred Lurmann, Kelley Meade, Denise Serebrisky, Shannon Thyne, William Rodriguez-CintronJose R. Rodriguez-Santana, L. Keoki Williams, Luisa N. Borrell, Esteban G. Burchard

Research output: Contribution to journalArticle

Abstract

Background: Among patients with asthma, the clinical effect and relative contribution of maternal smoking during pregnancy (in utero smoking) and current secondhand smoke (SHS) exposure on asthma control is poorly documented, and there is a paucity of research involving minority populations. Objectives: We sought to examine the association between poor asthma control and in utero smoking and current SHS exposure among Latino and black children with asthma. Methods: We performed a case-only analysis of 2 multicenter case-control studies conducted from 2008-2010 with similar protocols. We recruited 2481 Latino and black subjects with asthma (ages 8-17 years) from the mainland United States and Puerto Rico. Ordinal logistic regression was used to estimate the effect of in utero smoking and current SHS exposures on National Heart, Lung, and Blood Institute-defined asthma control. Results: Poor asthma control among children 8 to 17 years of age was independently associated with in utero smoking (odds ratio [OR], 1.5; 95% CI, 1.1-2.0). In utero smoking through the mother was also associated with secondary asthma outcomes, including early-onset asthma (OR, 1.7; 95% CI, 1.1-2.4), daytime symptoms (OR, 1.6; 95% CI, 1.1-2.1), and asthma-related limitation of activities (OR, 1.6; 95% CI, 1.2-2.2). Conclusions: Maternal smoking while in utero is associated with poor asthma control in black and Latino subjects assessed at 8-17 years of age.

Original languageEnglish (US)
Pages (from-to)1478-1483
Number of pages6
JournalThe Journal of Allergy and Clinical Immunology
Volume129
Issue number6
DOIs
StatePublished - Jun 2012

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Tobacco Smoke Pollution
Hispanic Americans
Asthma
Smoking
Odds Ratio
Mothers
National Heart, Lung, and Blood Institute (U.S.)
Puerto Rico
Case-Control Studies
Logistic Models

Keywords

  • asthma
  • health status disparities
  • prenatal exposure delayed effects
  • Secondhand smoke

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Oh, S. S., Tcheurekdjian, H., Roth, L. A., Nguyen, E. A., Sen, S., Galanter, J. M., ... Burchard, E. G. (2012). Effect of secondhand smoke on asthma control among black and Latino children. The Journal of Allergy and Clinical Immunology, 129(6), 1478-1483. https://doi.org/10.1016/j.jaci.2012.03.017

Effect of secondhand smoke on asthma control among black and Latino children. / Oh, Sam S.; Tcheurekdjian, Haig; Roth, Lindsey A.; Nguyen, Elizabeth A.; Sen, Saunak; Galanter, Joshua M.; Davis, Adam; Farber, Harold J.; Gilliland, Frank D.; Kumar, Rajesh; Avila, Pedro C.; Brigino-Buenaventura, Emerita; Chapela, Rocio; Ford, Jean G.; Lenoir, Michael A.; Lurmann, Fred; Meade, Kelley; Serebrisky, Denise; Thyne, Shannon; Rodriguez-Cintron, William; Rodriguez-Santana, Jose R.; Williams, L. Keoki; Borrell, Luisa N.; Burchard, Esteban G.

In: The Journal of Allergy and Clinical Immunology, Vol. 129, No. 6, 06.2012, p. 1478-1483.

Research output: Contribution to journalArticle

Oh, SS, Tcheurekdjian, H, Roth, LA, Nguyen, EA, Sen, S, Galanter, JM, Davis, A, Farber, HJ, Gilliland, FD, Kumar, R, Avila, PC, Brigino-Buenaventura, E, Chapela, R, Ford, JG, Lenoir, MA, Lurmann, F, Meade, K, Serebrisky, D, Thyne, S, Rodriguez-Cintron, W, Rodriguez-Santana, JR, Williams, LK, Borrell, LN & Burchard, EG 2012, 'Effect of secondhand smoke on asthma control among black and Latino children', The Journal of Allergy and Clinical Immunology, vol. 129, no. 6, pp. 1478-1483. https://doi.org/10.1016/j.jaci.2012.03.017
Oh, Sam S. ; Tcheurekdjian, Haig ; Roth, Lindsey A. ; Nguyen, Elizabeth A. ; Sen, Saunak ; Galanter, Joshua M. ; Davis, Adam ; Farber, Harold J. ; Gilliland, Frank D. ; Kumar, Rajesh ; Avila, Pedro C. ; Brigino-Buenaventura, Emerita ; Chapela, Rocio ; Ford, Jean G. ; Lenoir, Michael A. ; Lurmann, Fred ; Meade, Kelley ; Serebrisky, Denise ; Thyne, Shannon ; Rodriguez-Cintron, William ; Rodriguez-Santana, Jose R. ; Williams, L. Keoki ; Borrell, Luisa N. ; Burchard, Esteban G. / Effect of secondhand smoke on asthma control among black and Latino children. In: The Journal of Allergy and Clinical Immunology. 2012 ; Vol. 129, No. 6. pp. 1478-1483.
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T1 - Effect of secondhand smoke on asthma control among black and Latino children

AU - Oh, Sam S.

AU - Tcheurekdjian, Haig

AU - Roth, Lindsey A.

AU - Nguyen, Elizabeth A.

AU - Sen, Saunak

AU - Galanter, Joshua M.

AU - Davis, Adam

AU - Farber, Harold J.

AU - Gilliland, Frank D.

AU - Kumar, Rajesh

AU - Avila, Pedro C.

AU - Brigino-Buenaventura, Emerita

AU - Chapela, Rocio

AU - Ford, Jean G.

AU - Lenoir, Michael A.

AU - Lurmann, Fred

AU - Meade, Kelley

AU - Serebrisky, Denise

AU - Thyne, Shannon

AU - Rodriguez-Cintron, William

AU - Rodriguez-Santana, Jose R.

AU - Williams, L. Keoki

AU - Borrell, Luisa N.

AU - Burchard, Esteban G.

PY - 2012/6

Y1 - 2012/6

N2 - Background: Among patients with asthma, the clinical effect and relative contribution of maternal smoking during pregnancy (in utero smoking) and current secondhand smoke (SHS) exposure on asthma control is poorly documented, and there is a paucity of research involving minority populations. Objectives: We sought to examine the association between poor asthma control and in utero smoking and current SHS exposure among Latino and black children with asthma. Methods: We performed a case-only analysis of 2 multicenter case-control studies conducted from 2008-2010 with similar protocols. We recruited 2481 Latino and black subjects with asthma (ages 8-17 years) from the mainland United States and Puerto Rico. Ordinal logistic regression was used to estimate the effect of in utero smoking and current SHS exposures on National Heart, Lung, and Blood Institute-defined asthma control. Results: Poor asthma control among children 8 to 17 years of age was independently associated with in utero smoking (odds ratio [OR], 1.5; 95% CI, 1.1-2.0). In utero smoking through the mother was also associated with secondary asthma outcomes, including early-onset asthma (OR, 1.7; 95% CI, 1.1-2.4), daytime symptoms (OR, 1.6; 95% CI, 1.1-2.1), and asthma-related limitation of activities (OR, 1.6; 95% CI, 1.2-2.2). Conclusions: Maternal smoking while in utero is associated with poor asthma control in black and Latino subjects assessed at 8-17 years of age.

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KW - health status disparities

KW - prenatal exposure delayed effects

KW - Secondhand smoke

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