Effect of preoperative fusidic acid on the normal eyelid and conjunctival bacterial flora

Peter B. Taylor, Khalid F. Tabbara, Eileen M. Burd

Research output: Contribution to journalArticle

Abstract

A randomised trial comparing the topical application of 1% fusidic acid with 0·3% gentamicin solution in the reduction of the normal preoperative lid and conjunctival microbial flora was performed. Forty patients awaiting cataract surgery were randomly divided into two groups consisting of 20 patients each. The first group received a 1% microcrystalline suspension of fusidic acid, the second 0·3% gentamicin to the preoperative eye every two hours between 0600 and 2400 daily for 48 hours preoperatively. Cultures were obtained from both the lid margins and the conjunctival sac of both groups prior to antibiotic therapy and again in the operating theatre before surgery. Microbiological identification and colony counts were performed by standard laboratory methods. Staphylococcus epidermidis was the commonest micro-organism isolated. Statistical analysis revealed no significant differences in the ability of a 1% microcrystalline suspension of fusidic acid and 0·3% gentamicin in eliminating or reducing the normal preoperative conjunctival or lid flora.

Original languageEnglish (US)
Pages (from-to)206-209
Number of pages4
JournalBritish Journal of Ophthalmology
Volume72
Issue number3
DOIs
StatePublished - 1988
Externally publishedYes

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Fusidic Acid
Eyelids
Gentamicins
Suspensions
Lacrimal Apparatus
Staphylococcus epidermidis
Cataract
Anti-Bacterial Agents
Therapeutics

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Emergency Medicine
  • Ophthalmology

Cite this

Effect of preoperative fusidic acid on the normal eyelid and conjunctival bacterial flora. / Taylor, Peter B.; Tabbara, Khalid F.; Burd, Eileen M.

In: British Journal of Ophthalmology, Vol. 72, No. 3, 1988, p. 206-209.

Research output: Contribution to journalArticle

Taylor, Peter B. ; Tabbara, Khalid F. ; Burd, Eileen M. / Effect of preoperative fusidic acid on the normal eyelid and conjunctival bacterial flora. In: British Journal of Ophthalmology. 1988 ; Vol. 72, No. 3. pp. 206-209.
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