Effect of postural changes and isometric exercise on Doppler-derived measurements of diastolic function in normal subjects

J. J. Kmetzo, G. D. Plotnick, J. S. Gottdiener

Research output: Contribution to journalArticle


To determine if simple maneuvers that occur in daily life, such as changes in body position and isometric handgrip exercise, affect Doppler-derived measurements of diastolic function, we studied 22 normal male subjects in the supine position at rest and during several postural manipulations and during handgrip exercise. Comparison of values obtained in the 80° upright tilt position with those obtained in the standard supine position revealed significant decreases in early diastolic flow velocity (peak E) (-25±3 percent; p

Original languageEnglish (US)
Pages (from-to)357-363
Number of pages7
Issue number2
Publication statusPublished - 1991
Externally publishedYes


ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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