"Leukocyte counts" of 4 patients with obstructive liver disease, performed with an electronic counter, were > 100,000 per cubic millimeter, while visual counts, performed with 0.1N HCl in a counting chamber, were < 15,000 per cubic millimeter. Red cells in diluted samples of their blood were found to be resistant to lysis by the saponin used to prepare samples for electronic counting. Resistance to lysis was eliminated by washing the red cells and was produced by suspension of normal red cells in patient's plasma. Resistance, which was conferred by the plasma lipoproteins of density 1.006 to 1.063, appeared to be due to the unusually high concentration of nonesterified cholesterol in this lipoprotein fraction.
|Original language||English (US)|
|Number of pages||5|
|Journal||The Journal of laboratory and clinical medicine|
|State||Published - Jun 1 1969|
ASJC Scopus subject areas
- Pathology and Forensic Medicine