Effect of lysergic acid diethylamide on larval growth

D. V. Siva Sankar, Arthur Kopelman, Peter Schilder, Eleanor Gold

Research output: Contribution to journalArticlepeer-review


LYSERGIC acid diethylamide is known to be hallucinogenic in man1 and to produce behavioural aberrations in experimental animals. When administered to spiders2, lysergic acid diethylamide improved the regularity and angles in the pattern of the web. In the liver fluke (Fasciola hepatica) lysergic acid diethylamide intensified the motility3. However, in most cases the effects of lysergic acid diethylamide decrease shortly after withdrawal of the drug. In humans the effects may persist as long as 24 hr. in many cases4. Increased resistance to lysergic acid diethylamide on repeated administration has been reported5. Our present investigation shows that incorporation of lysergic acid diethylamide with the food caused marked reduction in growth of larvæ of Tenebrio molitar, which was not reversed by returning the larvæ to normal diet.

Original languageEnglish (US)
Pages (from-to)153-154
Number of pages2
Issue number4732
StatePublished - Dec 1 1960
Externally publishedYes

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