Procyclic Trypanosoma brucei cells were synchronized with 0.2 mM hydroxyurea. The cells did not arrest at the G1/S boundary but proceeded through one round of replication and arrested near the end of S phase. The mitochondrial genome (kinetoplast DNA network) replicated, forming two progeny networks, but the repair of minicircle gaps was inhibited.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Feb 2008|
ASJC Scopus subject areas
- Molecular Biology