Effect of human hydrosalpinx fluid on murine embryo development and implantation

Vanessa J. Rawe, Mary G. Compton, Jiaen Liu, Jairo E. García, Stefanie Shaffer, Eugene Katz

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


Objective: To determine the effect of hydrosalpinx fluid-containing medium on murine embryo development and implantation. Design: The development of one-, two-, and four-cell mouse embryos in medium containing 5%, 10%, and 20% of human hydrosalpinx fluid was observed. Implantation rates of mouse embryos transferred into the uterine horn with hydrosalpinx fluid-containing media were determined. Setting: Private hospital-based fertility center and IVF program. Main Outcome Measure(s): Percentage of embryos continuing cell division and implantation rates after ET. Result(s): Hydrosalpinx fluid in culture medium affected embryo development in a dose-dependent fashion. The injection of hydrosalpinx fluid-containing medium into the uterine horn did not affect embryo implantation. Conclusion(s): Hydrosalpinx fluid negatively affects murine embryo development, but its presence in the uterine horn at ET did not affect implantation.

Original languageEnglish (US)
Pages (from-to)668-670
Number of pages3
JournalFertility and sterility
Issue number4
StatePublished - Oct 1997


  • Embryo
  • Hydrosalpinx
  • IVF
  • Implantation

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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