Effect of fiducial configuration on target registration error in intraoperative cone-beam CT guidance of head and neck surgery

Nathaniel M. Hamming, Michael J. Daly, Jonathan C. Irish, Jeffrey H. Siewerdsen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Advances in image-guided surgery have led to minimally-invasive, high-precision procedures that increase the efficacy of treatment, minimize surgical complications, and reduce patient recovery time. A recent advance in intraoperative 3D imaging includes cone-beam CT (CBCT) implemented on a mobile C-arm. This paper investigates the effect of the number and configuration of fiducials on target registration error (TRE) and identifies fiducial configurations that minimize TRE for rigid point-based registration in CBCT-guided head and neck surgery. Best configurations were those that minimized the distance between the centroid of fiducials and the surgical target while maximizing fiducial separation (distance from principal axes). Configurations with as few as 4 fiducials could be identified that minimized TRE (e.g., TRE < 0.3 mm for the pituitary, cochlea, and nasion), with more fiducials (6 or more) providing improved TRE uniformity throughout the volume of clinical interest. If possible, fiducials affixed to the skin or cranium (e.g., 4-6 markers) should include a majority about the target (to minimize centroid-to-target distance) with others at a distance (to maximize separation). A greater number of fiducials distributed evenly can provide low, uniform TRE for all targets - e.g., 8 markers, TRE ∼0.2-0.6 mm throughout the volume of interest. Such work helps guide the implementation of C-arm CBCT in head and neck surgery in a manner that maximizes surgical precision and exploits intraoperative image guidance to its full potential.

Original languageEnglish (US)
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Pages3643-3648
Number of pages6
StatePublished - Dec 1 2008
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: Aug 20 2008Aug 25 2008

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Other

Other30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period8/20/088/25/08

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ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Hamming, N. M., Daly, M. J., Irish, J. C., & Siewerdsen, J. H. (2008). Effect of fiducial configuration on target registration error in intraoperative cone-beam CT guidance of head and neck surgery. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 3643-3648). [4649997] (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").