@article{f9195afb666143e1916558f8bf721127,
title = "Effect of Exercise and Rehabilitation Therapy on Risk of Hospitalization in Parkinson's Disease",
abstract = "Background: Exercise and physical therapy (PT) can improve motor function and quality of life in individuals with Parkinson's disease (PD), but their role in hospitalization avoidance is not well-studied. Objectives: To determine the longitudinal and temporal association of exercise and PT use with hospital encounter. Methods: Longitudinal regression and χ2 analyses were performed on Parkinson's Foundation Parkinson's Outcome Project exercise and PT use data from 4674 and 9259 persons with PD, respectively. Results: Greater exercise duration and intensity were associated with reduced odds of hospital encounter, whereas both PT and occupational therapy use were associated with increased odds. In the 2 years before a hospital encounter, there was an increased frequency of PT use, but not reductions in exercise. Conclusions: Consistent exercise may reduce hospitalization risk whereas PT referral may identify at-risk individuals without preventing this outcome. Further work to incentivize consistent exercise in PD may reduce healthcare use.",
keywords = "exercise, hospitalization, rehabilitation",
author = "Kannarkat, {George T.} and Rafferty, {Miriam R.} and Sheng Luo and Hongliang Liu and Mills, {Kelly A.}",
note = "Funding Information: K.A.M has received grant support from the National Institutes of Health (NIH)/National Institute of Neurological Disorders and Stroke NINDS, the Michael J. Fox Foundation, the RMS Family Foundation, Parkinson's Foundation, and research funding from Voyager Therapeutics and Global Kinetics Corporation. M.R.R. has received grant support related to this work from the NIH National Institute on Aging (P30AG059988, PI Linder and Wolf) and the United States Department of Defense (W81XWH‐20‐1‐0231). She has received funding on unrelated topics from Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Disability, Independent Living, and Rehabilitation Research; and the Parkinson's Foundation. She receives honorarium for service to the Parkinson's Foundation related to the Parkinson's Outcomes Project, physical therapy, and exercise initiatives. The research of S.L. was supported by National Institute of Aging (R01AG064803, P30AG072958, and P30AG028716), Parkinson's Foundation, and CHDI Foundation. Funding Sources and Conflicts of Interest: Funding Information: K.A.M. has received grant support from the National Institutes of Health (NIH)/ NINDS, the Michael J. Fox Foundation, the RMS Family Foundation, Parkinson's Foundation, and research funding from Voyager Therapeutics and Global Kinetics Corporation. M.R.R. has received grant support related to this work from the NIH National Institute on Aging (P30AG059988, PI Linder and Wolf) and the United States Department of Defense (W81XWH‐20‐1‐0231). She has received funding on unrelated topics from Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Disability, Independent Living, and Rehabilitation Research; and the Parkinson's Foundation. She receives honorarium for service to the Parkinson's Foundation related to the Parkinson's Outcomes Project, physical therapy, and exercise initiatives. The research of S.L. was supported by National Institute of Aging (R01AG064803, P30AG072958, and P30AG028716), Parkinson's Foundation, and CHDI Foundation. Financial Disclosures for the Previous 12 Months: Publisher Copyright: {\textcopyright} 2022 International Parkinson and Movement Disorder Society.",
year = "2022",
month = may,
doi = "10.1002/mdc3.13456",
language = "English (US)",
volume = "9",
pages = "494--500",
journal = "Movement Disorders Clinical Practice",
issn = "2330-1619",
publisher = "John Wiley and Sons Ltd",
number = "4",
}