Several ergot derivatives (lergotrile, Sandoz compound 29-712, and metergoline) prolonged the latency and shortened the duration of the post-decapitation convulsions in rats. Other ergot derivatives, such as bromocriptine and lisuride, were ineffective. The decrease in the duration of the post-decapitation convulsion was related to the ratio of the in vitro inhibition of norepinephrine and dopamine receptor binding.
|Original language||English (US)|
|Number of pages||6|
|Journal||Communications In Psychopharmacology|
|State||Published - 1980|
ASJC Scopus subject areas