TY - JOUR
T1 - Effect of early diagnosis and treatment with percutaneous lead extraction on survival in patients with cardiac device infections
AU - Viganego, Federico
AU - O'Donoghue, Susan
AU - Eldadah, Zayd
AU - Shah, Manish H.
AU - Rastogi, Mohit
AU - Mazel, Jay A.
AU - Platia, Edward V.
PY - 2012/5/15
Y1 - 2012/5/15
N2 - Cardiac device infections (CDIs) represent a serious complication after the implantation of pacemakers and defibrillators. In addition to antimicrobials, complete hardware removal, mostly with percutaneous lead extraction (PLE), is necessary to limit recurrences. However, CDI diagnosis is often difficult and is sometimes delayed, and scarce data exist on how the timing of PLE may affect clinical outcomes. In this study, the in-hospital outcomes of 52 consecutive patients with CDIs who underwent PLE were retrospectively analyze. Co-morbidities such as diabetes mellitus, congestive heart failure, renal insufficiency, and end-stage renal disease were highly prevalent in the study cohort. Patients were divided into group A (bacteremia or device endocarditis) and group B (localized pocket infection). In-hospital mortality was 29% in group A and 5% in group B (p = 0.02) and was due mostly to sepsis. Hospital stays were shorter in group B patients (5.7 vs 21.7 days, p
AB - Cardiac device infections (CDIs) represent a serious complication after the implantation of pacemakers and defibrillators. In addition to antimicrobials, complete hardware removal, mostly with percutaneous lead extraction (PLE), is necessary to limit recurrences. However, CDI diagnosis is often difficult and is sometimes delayed, and scarce data exist on how the timing of PLE may affect clinical outcomes. In this study, the in-hospital outcomes of 52 consecutive patients with CDIs who underwent PLE were retrospectively analyze. Co-morbidities such as diabetes mellitus, congestive heart failure, renal insufficiency, and end-stage renal disease were highly prevalent in the study cohort. Patients were divided into group A (bacteremia or device endocarditis) and group B (localized pocket infection). In-hospital mortality was 29% in group A and 5% in group B (p = 0.02) and was due mostly to sepsis. Hospital stays were shorter in group B patients (5.7 vs 21.7 days, p
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U2 - 10.1016/j.amjcard.2012.01.360
DO - 10.1016/j.amjcard.2012.01.360
M3 - Article
C2 - 22356796
AN - SCOPUS:84860459335
SN - 0002-9149
VL - 109
SP - 1466
EP - 1471
JO - The American Journal of Cardiology
JF - The American Journal of Cardiology
IS - 10
ER -