Effect of early diagnosis and treatment with percutaneous lead extraction on survival in patients with cardiac device infections

Federico Viganego, Susan O'Donoghue, Zayd Eldadah, Manish H. Shah, Mohit Rastogi, Jay A. Mazel, Edward V. Platia

Research output: Contribution to journalArticlepeer-review

Abstract

Cardiac device infections (CDIs) represent a serious complication after the implantation of pacemakers and defibrillators. In addition to antimicrobials, complete hardware removal, mostly with percutaneous lead extraction (PLE), is necessary to limit recurrences. However, CDI diagnosis is often difficult and is sometimes delayed, and scarce data exist on how the timing of PLE may affect clinical outcomes. In this study, the in-hospital outcomes of 52 consecutive patients with CDIs who underwent PLE were retrospectively analyze. Co-morbidities such as diabetes mellitus, congestive heart failure, renal insufficiency, and end-stage renal disease were highly prevalent in the study cohort. Patients were divided into group A (bacteremia or device endocarditis) and group B (localized pocket infection). In-hospital mortality was 29% in group A and 5% in group B (p = 0.02) and was due mostly to sepsis. Hospital stays were shorter in group B patients (5.7 vs 21.7 days, p

Original languageEnglish (US)
Pages (from-to)1466-1471
Number of pages6
JournalThe American Journal of Cardiology
Volume109
Issue number10
DOIs
StatePublished - May 15 2012
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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