Effect of diabetic serum factor on polymorphonuclear leucocyte membrane hydrophobicity and particle internalisation

S. Biswas, A. Bhelwa, A. Itoop, S. Biswal, N. Nath

Research output: Contribution to journalArticle

Abstract

Membrane hydrophobicity and slalidase activity of normal Poly morphonuclear Leucocyte were significantly enhanced when incubated with DSF. As a consequence, internalisation of E. coli and S. aureus (opsonised or unopsonised) were greatly dimnished, internalisation of E. coli being higher in either category. Although, increase in hydrophobicity of the membrane correlated well with the time of decrease of particle internalisation (both at 30 min.), enhancement of sialidase activity did not coincide with the said alterations.

Original languageEnglish (US)
Pages (from-to)9-12
Number of pages4
JournalIndian Journal of Clinical Biochemistry
Volume9
Issue number1
DOIs
StatePublished - Sep 1 1994
Externally publishedYes

Keywords

  • PMNL. contact angle
  • membrane hydrophobicity
  • particle internalisation
  • zeta potential

ASJC Scopus subject areas

  • Clinical Biochemistry

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