Effect of continued oral feeding on clinical and nutritional outcomes of acute diarrhea in children

Kenneth H. Brown, Arturo S. Gastañaduy, Jose M. Saavedra, Jorge Lembcke, Diana Rivas, Alastair D. Robertson, Robert Yolken, R. Bradley Sack

Research output: Contribution to journalArticlepeer-review


One hundred twenty-eight nonmalnourished male patients between 3 and 36 months of age were randomly assigned to receive one of four lactose-free dietary treatments to determine the effect of dietary therapy on the severity and nutritional outcome of diarrheal illness. Group 1 received a formula diet composed of casein, sucrose, dextrin with maltose (Dextri-Maltose), and vegetable oll to provide 110 kcal/kg body weight/d (CSO-110). Group 2 received CSO to provide 55 kcal/kg/d (CSO-55) for 2 days and then CSO-110. Group 3 received only oral glucose-electrolyte solution (GES) for 2 days, CSO-55 for the next 2 days, and then CSO-110. Group 4 received the same diets as Group 3 except that only intravenous GES was used for the first 2 days. The GES maintenance solutions provided 24 to 30 kcal/kg/d. Therapeutic success rates were similar among dietary groups, ranging from 90% to 97%. Fecal excretion was initially lower in group 4 (P<0.05) but was similar initially among groups treated orally and among all four groups beginning on day 3. Net apparent absorption of nitrogen, fat, carbohydrate, and total energy; retention of nitrogen; and increments in body weight, arm circumference, and skin-fold thicknesses were positively related to the amounts of dietary energy consumed. Thus continued oral feeding with the CSO diets during the early phase of therapy yielded improved nutritional results.

Original languageEnglish (US)
Pages (from-to)191-200
Number of pages10
JournalThe Journal of pediatrics
Issue number2
StatePublished - Feb 1988

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Effect of continued oral feeding on clinical and nutritional outcomes of acute diarrhea in children'. Together they form a unique fingerprint.

Cite this