Effect of childhood obesity prevention programmes on blood lipids: A systematic review and meta-analysis

L. Cai, Y. Wu, L. J. Cheskin, R. F. Wilson, Y. Wang

Research output: Contribution to journalArticle

Abstract

We aimed to assess the effects of childhood obesity prevention programmes on blood lipids in high-income countries. We searched MEDLINE®, Embase, PsychInfo, CINAHL®, clinicaltrials.gov, and the Cochrane Library up to 22 April 2013 for relevant randomized controlled trials, quasi-experimental studies and natural experiments published in English. Studies were included if they implemented diet and/or physical activity intervention(s) with ≥1 year follow-up (or ≥6 months for school-based intervention studies) in 2-18-year-olds, and were excluded if they targeted only overweight/obese children, or those with a pre-existing medical condition. Seventeen studies were finally included. For total cholesterol, the pooled intervention effect was -0.97mgdL-1 [95% confidence interval (CI): -3.26, 1.32; P=0.408]; for low-density lipoprotein cholesterol (LDL-C), -6.06mgdL-1 (95% CI: -11.09, -1.02; P=0.018); for high-density lipoprotein cholesterol (HDL-C), 1.87mgdL-1 (95% CI: 0.39, 3.34; P=0.013); and for triglycerides, -1.95mgdL-1 (95% CI: -4.94, 1.04; P=0.202). Most interventions (70%) showed similar significant or no effects on adiposity- and lipids outcomes: 15% interventions improved both adiposity- and lipids outcomes; 55% had no significant effects on either. Childhood obesity prevention programmes had a significant desirable effect on LDL-C and HDL-C. Two-thirds of interventions showed similar significant or no effects in adiposity- and lipids outcomes. Assessing lipids outcomes provide additional useful information on obesity prevention programme benefits.

Original languageEnglish (US)
Pages (from-to)933-944
Number of pages12
JournalObesity Reviews
Volume15
Issue number12
DOIs
StatePublished - Dec 1 2014

Keywords

  • Child
  • Lipids
  • Obesity
  • Prevention

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Public Health, Environmental and Occupational Health

Fingerprint Dive into the research topics of 'Effect of childhood obesity prevention programmes on blood lipids: A systematic review and meta-analysis'. Together they form a unique fingerprint.

  • Cite this