Effect of apolipoprotein E polymorphism on fasting retinyl palmitate level

Andrei P. Surguchov, Eric Boerwinkle, A. Richey Sharrett, Wolfgang Patsch

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of apolipoprotein E (apo E) common genotypes on fasting retinyl palmitate (RP) level was studied in 344 white individuals, of which 130 had intimal thickening of the carotid artery ("cases") and 214 were controls. In this sample the common apo E genotypes possessed a statistically significant effect on fasting RP level in cases, while in controls the effect observed was not statistically significant. It is suggested that the effect of apo E may be expressed at the level of remnant clearance particles. Additionally, in cases other traits interact with the apo E genotype to influence fasting RP level.

Original languageEnglish (US)
Pages (from-to)156-157
Number of pages2
JournalBiochemical and Molecular Medicine
Volume55
Issue number2
DOIs
StatePublished - Aug 1995

ASJC Scopus subject areas

  • Biochemistry

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