The effect of antiretroviral therapy (ART) on chloroquine and desethyl-chloroquine plasma concentrations was evaluated in clinical trial participants. Concentrations did not differ among participants receiving protease inhibitor-based ART (n = 9), efavirenz-based ART (n = 15), or other ART (n = 8) and those not receiving ART (n = 31). Efavirenz seemed to inhibit chloroquine desethylation.
|Original language||English (US)|
|Number of pages||4|
|Journal||Clinical infectious diseases : an official publication of the Infectious Diseases Society of America|
|State||Published - Oct 30 2018|
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases