Effect of age on response to amblyopia treatment in children

Jonathan M. Holmes, Elizabeth L. Lazar, B. Michele Melia, William F. Astle, Linda R. Dagi, Sean P. Donahue, Marcela G. Frazier, Richard W. Hertle, Michael X Repka, Graham E. Quinn, Katherine K. Weise

Research output: Contribution to journalArticle

Abstract

Objective: To determine whether age at initiation of treatment for amblyopia influences the response among children 3 to less than 13 years of age with unilateral amblyopia who have 20/40 to 20/400 amblyopic eye visual acuity. Methods: A meta-analysis of individual subject data from 4 recently completed randomized amblyopia treatment trials was performed to evaluate the relationship between age and improvement in logMAR amblyopic eye visual acuity. Analyses were adjusted for baseline amblyopic eye visual acuity, spherical equivalent refractive error in the amblyopic eye, type of amblyopia, prior amblyopia treatment, study treatment, and protocol. Age was categorized (3 to

Original languageEnglish (US)
Pages (from-to)1451-1457
Number of pages7
JournalArchives of Ophthalmology
Volume129
Issue number11
DOIs
StatePublished - Nov 2011

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Amblyopia
Visual Acuity
Therapeutics
Refractive Errors
Clinical Protocols
Meta-Analysis

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Holmes, J. M., Lazar, E. L., Melia, B. M., Astle, W. F., Dagi, L. R., Donahue, S. P., ... Weise, K. K. (2011). Effect of age on response to amblyopia treatment in children. Archives of Ophthalmology, 129(11), 1451-1457. https://doi.org/10.1001/archophthalmol.2011.179

Effect of age on response to amblyopia treatment in children. / Holmes, Jonathan M.; Lazar, Elizabeth L.; Melia, B. Michele; Astle, William F.; Dagi, Linda R.; Donahue, Sean P.; Frazier, Marcela G.; Hertle, Richard W.; Repka, Michael X; Quinn, Graham E.; Weise, Katherine K.

In: Archives of Ophthalmology, Vol. 129, No. 11, 11.2011, p. 1451-1457.

Research output: Contribution to journalArticle

Holmes, JM, Lazar, EL, Melia, BM, Astle, WF, Dagi, LR, Donahue, SP, Frazier, MG, Hertle, RW, Repka, MX, Quinn, GE & Weise, KK 2011, 'Effect of age on response to amblyopia treatment in children', Archives of Ophthalmology, vol. 129, no. 11, pp. 1451-1457. https://doi.org/10.1001/archophthalmol.2011.179
Holmes JM, Lazar EL, Melia BM, Astle WF, Dagi LR, Donahue SP et al. Effect of age on response to amblyopia treatment in children. Archives of Ophthalmology. 2011 Nov;129(11):1451-1457. https://doi.org/10.1001/archophthalmol.2011.179
Holmes, Jonathan M. ; Lazar, Elizabeth L. ; Melia, B. Michele ; Astle, William F. ; Dagi, Linda R. ; Donahue, Sean P. ; Frazier, Marcela G. ; Hertle, Richard W. ; Repka, Michael X ; Quinn, Graham E. ; Weise, Katherine K. / Effect of age on response to amblyopia treatment in children. In: Archives of Ophthalmology. 2011 ; Vol. 129, No. 11. pp. 1451-1457.
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