Abstract
Levels of plasma calcium, phosphorus, creatinine and 1,25-(OH)2-D were measured in healthy male Sprague-Dawley rats aged 6 months (mature) and 20-24 months (senescent). Plasma 1,25-(OH)2-D levels fell from 95 ± 50 pmol/l in the mature rats to 41 ± 10 pmol/l in the senescent rats (p < 0.01). Despite a significant fall in plasma phosphate from 3.06 ± 0.37 mmol/l to 2.54 mmol/l (p < 0.005) in the two groups, respectively, plasma calcium remained constant at about 2.4 mmol/l in both groups.
Original language | English (US) |
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Pages (from-to) | 54-56 |
Number of pages | 3 |
Journal | AGE |
Volume | 5 |
Issue number | 2 |
DOIs | |
State | Published - Apr 1982 |
Externally published | Yes |
ASJC Scopus subject areas
- Aging
- Geriatrics and Gerontology